GSE111059 Gene expression of cardiac fibroblasts post-MI

Contributors : Xing Fu ; Vikram Prasad ; Jeffery MolkentinSeries Type : Expression profiling by arrayOrganism : Mus musculusCardiac fibroblasts stay relatively quiescent under normal condition. These cells differentiate to myofibroblasts after myocardial infarction (MI), characterized by the expression of contractile proteins and secretion of elevated levels of extracellular matrix proteins, leading to cardiac remodeling. The differentiated myofiroblasts gradually lose most myofibroblast phenotypes but still persist in the infarct area to maintain the tissue structural integrity.We used microarrays to reveal the change in cardiac fibroblast gene expression profile after MI.

Source: GEO: Gene Expression Omnibus - February 24, 2018 Category: Genetics & Stem Cells Tags: Expression profiling by array Mus musculus Source Type: research