Objective assessment of physical activity and sedentary behaviour in knee osteoarthritis patients – beyond daily steps and total sedentary time

Knee osteoarthritis patients may become physically inactive due to pain and functional limitations. Whether physical activity exerts a protective or harmful effect depends on the frequency, intensity, time and...
Source: BMC Musculoskeletal Disorders - Category: Orthopaedics Authors: Tags: Research article Source Type: research

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Source: Journal of Pain Research - Category: Anesthesiology Tags: Journal of Pain Research Source Type: research
Publication date: January–February 2020Source: Revista Española de Cirugía Ortopédica y Traumatología (English Edition), Volume 64, Issue 1Author(s): A. Abarquero-Diezhandino, G. Luengo-Alonso, D. Alonso-Tejero, E.J. Sánchez-Morata, C. Olaya-Gonzalez, J. Vilá y RicoAbstractBackground and aimsAt least 10% of ankle fractures involve the posterior malleolus of the tibia, which has been related to poorer long-term prognosis. Our aim was to analyse the clinical and functional outcomes of ankle fractures involving the posterior edge, treated surgically without direct reduction of t...
Source: Revista Espanola de Cirugia Ortopedica y Traumatologia - Category: Orthopaedics Source Type: research
l V. Vitiello Wrist actigraphy has been used to assess sleep in older adult populations for nearly half a century. Over the years, the continuous raw activity data derived from actigraphy has been used for the characterization of factors beyond sleep/wake such as physical activity patterns and circadian rhythms. Behavioral activity rhythms (BAR) are useful to describe individual daily behavioral patterns beyond sleep and wake, which represent important and meaningful clinical outcomes. This paper reviews common rhythmometric approaches and summarizes the available data from the use of these different approaches in olde...
Source: Sensors - Category: Biotechnology Authors: Tags: Review Source Type: research
ConclusionsKT plus quadriceps strengthening exercise does not offer advantages for improvement of pain compared with quadriceps strengthening exercise alone in knee OA.ResumenAntecedentesLos efectos benéficos del ejercicio en el tratamiento de la osteoartritis (OA) de rodilla han sido verificados en varios estudios. El vendaje kinesiológico o kinesiotaping (KT) se ha popularizado debido a la reducción de la presión local y el aumento de la circulación, lo que resulta en disminución del dolor.ObjetivoDeterminar la efectividad clínica de la terapia de fortalecimiento en conjun...
Source: Reumatologia Clinica - Category: Rheumatology Source Type: research
Conclusion. This large systematic review of over 11,000 participants demonstrates that topical diclofenac is effective for acute pain, such as sprains and strains, with minimal AEs. The effectiveness of topical diclofenac was also demonstrated in chronic musculoskeletal pain, such as osteoarthritis, but with a higher NNT (worse) compared with acute pain. Again, the incidence of AEs was low. Formulation does play a part in effectiveness, and studies are needed to investigate this further. Studies of chronic pain outside of osteoarthritis would also be helpful. PMID: 31944135 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
ConclusionDesign modifications to improve patellofemoral mechanics demonstrated significant improvements in overall pain and patellofemoral pain and reduced manipulation rates post-operatively.
Source: HSS Journal - Category: Orthopaedics Source Type: research
Link N suppresses interleukin-1β-induced biological effects on human osteoarthritic cartilage. Eur Cell Mater. 2020 Jan 15;39:65-76 Authors: Alaqeel M, Grant MP, Epure LM, Salem O, AlShaer A, Huk OL, Bergeron SG, Zukor DJ, Kc R, Im HJ, Anbazhagan AN, Antoniou J, Mwale F Abstract Osteoarthritis (OA) is a disease of diarthrodial joints associated with extracellular matrix proteolytic degradation under inflammatory conditions, pain and disability. Currently, there is no therapy to prevent, reverse or modulate the disease course. The present study aimed at evaluating the regenerative potential of Link...
Source: European Cells and Materials - Category: Cytology Tags: Eur Cell Mater Source Type: research
Osteoarthritis (OA), degeneration of cartilage associated with aging, lifestyle, and trauma, is one of the most common diseases that leads to lower quality of life and socioeconomic burden in the United States. Clinically, OA is initially managed by non-steroidal anti-inflammatory drugs, but eventually requires surgical intervention to reduce pain and increase function. Cartilage is a mechanotransductive tissue and requires a mechanical stimulus to sustain its mechanical and physiologic properties.
Source: Ultrasound in Medicine and Biology - Category: Radiology Authors: Tags: Review Article Source Type: research
J Knee Surg DOI: 10.1055/s-0039-1700978To improve the long-term outcomes of high tibial osteotomy (HTO) for gonarthritis, many cartilage repair procedures appeared, but their effects were controversial. To evaluate the efficacy of cartilage repair procedures during HTO for gonarthritis, we performed this update meta-analysis. We performed the system retrieval for clinical trials using various databases and then pooled the outcomes of the included studies. Fifteen studies were involved. The pooled results indicated that there were no significant differences in Kellgren and Lawrence (KL) scale (mean difference [MD] =&...
Source: Journal of Knee Surgery - Category: Orthopaedics Authors: Tags: Original Article Source Type: research
ConclusionsTolerability of opioids is low and efficacy is not clinically relevant in controlled studies from 4 to 24  weeks for osteoarthritis pain.SignificanceWithin the context of randomized controlled trials (4 –24 weeks), opioids provided no clinically relevant pain relief and no clinically relevant reduction in disability compared with placebo in chronic osteoarthritis pain (hip, knee). Number needed to treat for an additional dropout due to side effects was 5 (95% confidence interval 4–7). Two stud ies found no signals of abuse and addiction. The frequency of serious adverse events including dea...
Source: European Journal of Pain - Category: Anesthesiology Authors: Tags: REVIEW ARTICLE Source Type: research
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