Isolated Orbital Metastasis as an Initial Presentation of a Breast Cancer

Publication date: Available online 23 February 2018 Source:Cirugía Española (English Edition) Author(s): Ismael Mora-Guzmán, Rocío Maqueda González, Beatriz Doblado Cardellach, Ana Rodríguez Sánchez
Source: Cirugia Espanola - Category: Surgery Source Type: research

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A. Praveena*, S. Arthi and B. Sudarmathi
Source: Indian Journal of Pharmaceutical Sciences - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 15 November 2019Source: Nanomedicine: Nanotechnology, Biology and MedicineAuthor(s): Chao Teng, Zhuodong Chai, Zhongyue Yuan, Lianjie Ren, Chenshi Lin, Zhen Yan, Wei He, Chao Qin, Lei Yang, Xiaopeng Han, Lifang YinAbstractPEG coating was regarded as one effective method to improve the tumor-targeting efficiency of hyaluronic acid-based nanoparticles (HBN). However, the research of interaction between PEG coating and different receptors such as stabilin-2 and CD44 was limited. Herein, we synthesized a series of PEGylated hyaluronic acid with Curcumin (PHCs) to evaluate the role of PEG coat...
Source: Nanomedicine: Nanotechnology, Biology and Medicine - Category: Nanotechnology Source Type: research
This study identifies mechanisms mediating responses to immune checkpoint inhibitors using mouse models of triple-negative breast cancer. By creating new mammary tumor models, we find that tumor mutation burden and specific immune cells are associated with response. Further, we developed a rich resource of single-cell RNA-seq and bulk mRNA-seq data of immunotherapy-treated and non-treated tumors from sensitive and resistant murine models. Using this, we uncover that immune checkpoint therapy induces T follicular helper cell activation of B cells to facilitate the anti-tumor response in these models. We also show that B cel...
Source: Cell - Category: Cytology Source Type: research
The objective was to test and assess the accuracy of a scoring method in probabilistic data linkage in order to enable automatic identification of true matches, dispensing with the manual inspection stage. Accuracy study using data from the Breast Cancer Information System (SISMAMA) base in Minas Gerais State, Brazil, from 2009 and 2010. After cleaning and standardization, a 16-step probabilistic linkage of the 2009 and 2010 databases was performed, where each step was inspected manually to obtain a gold standard. Samples were then selected, inspected, and assessed to calculate the method's accuracy in selecting true match...
Source: Cadernos de Saude Publica - Category: International Medicine & Public Health Authors: Tags: Cad Saude Publica Source Type: research
Programming the hospital electronic health record (EHR) system to notify clinicians...Read more on AuntMinnie.comRelated Reading: High-risk women should start breast screening earlier Smokers less likely to undergo medical, screening exams Patient navigation boosts women's screening compliance Breast cancer drives disparity between younger men, women Earlier colon screening saves lives -- but at what cost?
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Abstract Introduction: Clinicopathologic and prognostic significance of body mass index (BMI) in breast cancer (BC) patients remained conflicting. We aimed to investigate and modify the impact of BMI on clinicopathological significance and survival in western Chinese BC patients. Materials and Methods: 8,394 female BC patients from Western China Clinical Cooperation Group (WCCCG) between 2005 and 2015 were identified. Multivariable logistic regression and Cox proportion hazard regressions were used to examine the difference of clinicopathologic and survival characteristics between BMI categories. Results...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Condition:   Breast Cancer Intervention:   Other: Progressive relaxation exercises Sponsor:   Hacettepe University Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSIONS Our study showed that conservative breast surgery is a reliable therapy for breast cancer patients during pregnancy, with similar DFS and OS compared to nonpregnant patients. PMID: 31725704 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Roche today announced that the European Medicines Agency ’s (EMA) Committee for Medicinal Products for Human Use (CHMP) has recommended the approval of Kadcyla® (trastuzumab emtansine) for the adjuvant (after surgery) treatment of adult patients with HER2-positive early breast cancer (eBC) who have residual invasive disease, in the breast and/or lymph nodes, after neoadjuvant (before surgery) taxane-based and HER2-targeted therapy.
Source: Roche Media News - Category: Pharmaceuticals Source Type: news
Conclusion: These findings cannot support contribution of rs1042522 polymorphism to breast cancer risk in an Iranian population. Future larger studies may help confirm this finding with a greater power. PMID: 31721533 [PubMed]
Source: Cancer Control - Category: Cancer & Oncology Authors: Tags: Cell J Source Type: research
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