Vulnerability of glia and vessels of rat substantia nigra in rotenone Parkinson model.

CONCLUSION: Our results demonstrated that oxidative stress and mitochondrial dysfunction involved nigral cellular elements other than dopaminergic neurons. These included astrocytes, microglia, vascular endothelial cells, and pericytes, which might result in promoting damage to the neurons.
PMID: 29466086 [PubMed - in process]

Source: Ultrastructural Pathology - February 23, 2018 Category: Pathology Authors: Elgayar SAM, Abdel-Hafez AAM, Gomaa AMS, Elsherif R Tags: Ultrastruct Pathol Source Type: research