Low ‐dose naltrexone: a novel treatment for Hailey–Hailey disease

We report a case of treatment‐resistant Hailey–Hailey disease having failed topical and oral steroids, prophylactic aciclovir and doxycycline, and systemic therapies including dapsone, acitretin and ciclosporin. Low‐dose naltrexone 4·5 mg once daily was commenced following an incidental benefit in this patient's similarly affected sister. The clinical and psychological response to date has been considerable.

Source: British Journal of Dermatology - February 23, 2018 Category: Dermatology Authors: V. Campbell, C. McGrath, A. Corry Tags: Case Report: Therapy Source Type: research