New crystal structures reveal mysterious mechanism of gene regulation by the 'magic spot'

(Penn State) Using an innovative crystallization technique for studying 3D structures of gene transcription machinery, researchers revealed new insights into the long debated action of the 'magic spot' -- a molecule that controls gene expression inE. coli and many other bacteria when the bacteria are stressed. The study contributes to fundamental understanding of how bacteria adapt and survive under adverse conditions and provides clues about key processes that could be targeted in the search for new antibiotics.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news