GSE98641 The expression of miRNAs is influenced by the infection of Helicobacter Pylori

Contributors : Matteo Pagliari ; Fabio Munari ; Silvia Lonardi ; Francesco Chemello ; Gaia Codolo ; Caterina Millino ; Beniamina Pacchioni ; William Vermi ; Matteo Fassan ; Marina de Bernard ; Stefano CagninSeries Type : Non-coding RNA profiling by arrayOrganism : Homo sapiensMacrophages are important cells involved in infections responses. They are mediators of gastritis in acute Helicobacter pylori (Hp) Infection and to identify how Hp affects macrophages response to infection we measured miRNA expression after macrophages Hp infection.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Non-coding RNA profiling by array Homo sapiens Source Type: research

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AbstractInfection withHelicobacter pylori (H. pylori) is highly prevalent worldwide, is typically acquired during childhood and, if left untreated, is the major cause of numerous complications, such as chronic gastritis and peptic ulcer disease. Management ofH. pylori infection in paediatric patients differs to that of adults, and should be tailored to the antimicrobial susceptibility profile of the patient in order to achieve optimal efficacy.
Source: Drugs and Therapy Perspectives - Category: Drugs & Pharmacology Source Type: research
Authors: Mohammadian T, Ganji L Abstract Helicobacter pylori causes one of the most common infections in human populations. The role of this bacterium in chronic gastritis, gastric ulcer, gastric cancer, as well as extra-digestive diseases such as ischemic heart disease and chronic obstructive pulmonary diseases, is well known. Prevention and control of these diseases can occur by early diagnosis and eradication of H. pylori infection. At present, different methods have been established to detect H. pylori infection. The biopsy-based tests, which are known as invasive methods, such as rapid urease test and histolog...
Source: Monoclonal Antibodies in Immunodiagnosis and Immunotherapy - Category: Microbiology Tags: Monoclon Antib Immunodiagn Immunother Source Type: research
ConclusionH. pylori dupA genotype is inversely associated with DU risk in this population.
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Conditions:   Helicobacter Pylori Infection;   Helicobacter Gastritis;   Helicobacter-Associated Pyloric Ulcer Intervention:   Drug: Rabeprazole Sponsor:   Chang Gung Memorial Hospital Enrolling by invitation
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusion: HP eradication is an effective initial therapy for FD. PG II value is considered a predictive factor for FD symptom improvement through HP eradication.Digestion
Source: Digestion - Category: Gastroenterology Source Type: research
Publication date: March 2019Source: Biomedicine &Pharmacotherapy, Volume 111Author(s): Raquel de Cássia dos Santos, Flavia Bonamin, Larissa Lucena Périco, Vinícius Peixoto Rodrigues, Ana Caroline Zanatta, Clenilson Martins Rodrigues, Miriam Sannomiya, Matheus Aparecido dos Santos Ramos, Bruna Vidal Bonifácio, Taís Maria Bauab, Jorge Tamashiro, Lúcia Regina Machado da Rocha, Wagner Vilegas, Clelia Akiko Hiruma-LimaAbstractByrsonima intermedia is a species of bush popularly used to treat gastrointestinal disorders, such as gastric ulcers, gastritis, and diarrhea. Previous studies...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 11 January 2019Source: Autoimmunity ReviewsAuthor(s): Sara Massironi, Alessandra Zilli, Alessandra Elvevi, Pietro InvernizziAbstractChronic autoimmune atrophic gastritis (CAAG) is an organ-specific autoimmune disease, which affects the corpus–fundus gastric mucosa. Although it has been described for several years, the real pathophysiological mechanisms, the natural history and the possible neoplastic complications are not completely known. Atrophy of the gastric mucosa is the endpoint of the chronic processes, with the loss of glandular cells and their replacement by intestinal-type...
Source: Autoimmunity Reviews - Category: Allergy & Immunology Source Type: research
Conclusions: Inpatient incidence and mortality for PCI-related GIB has been increasing particularly with a large increase in incidence among older patients. A multidisciplinary approach focused on risk-stratifying patients may improve preventable causes of GIB.
Source: Journal of Clinical Gastroenterology - Category: Gastroenterology Tags: ALIMENTARY TRACT: Original Articles Source Type: research
Publication date: Available online 3 January 2019Source: Journal of EthnopharmacologyAuthor(s): Karuppusamy Arunachalam, Amilcar Sabino Damazo, Eduarda Pavan, Darley Maria Oliveira, Fabiana de Freitas Figueiredo, Marco Tulio Marra Machado, Balogun Sikiru Olaitan, Ilsamar Mendes Soares, Robson dos Santos Barbosa, Tarso da Costa Alvim, Sérgio Donizeti Ascêncio, Domingos Tabajara de Oliveira MartinsAbstractEthnopharmacological relevanceCochlospermum regium (Bixaceae) is a native shrub of Brazil and its xylopodium (infusion/decoction) is being used for the treatment of gastritis, ulcers, arthritis, intestinal infe...
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Authors: White JR, Sami SS, Reddiar D, Mannath J, Ortiz-Fernández-Sordo J, Beg S, Scott R, Thiagarajan P, Ahmad S, Parra-Blanco A, Kasi M, Telakis E, Sultan AA, Davis J, Figgins A, Kaye P, Robinson K, Atherton JC, Ragunath K Abstract BACKGROUND: Patient outcomes in gastric adenocarcinoma are poor due to late diagnosis. Detecting and treating at the premalignant stage has the potential to improve this. Helicobacter pylori is also a strong risk factor for this disease. AIMS: Primary aims were to assess the diagnostic accuracy of magnified narrow band imaging (NBI-Z) endoscopy and serology in detecting norm...
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
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