[Correspondence] Xpert Ultra's place in the diagnosis of tuberculous meningitis

I read with interest the report1 by Nathan Bahr and colleagues describing the diagnostic accuracy of Xpert Ultra for tuberculous meningitis. Current WHO guidelines to use Xpert MTB/RIF as the initial investigation for tuberculous meningitis have been criticised because the sensitivity and negative predictive value are often too low to confidently rule out tuberculous meningitis.2 If the higher sensitivity of Xpert Ultra is confirmed, the test is likely to be useful as a rule-out test in a broader range of patients.

Source: The Lancet Infectious Diseases - February 22, 2018 Category: Infectious Diseases Authors: Tom Boyles Tags: Correspondence Source Type: research