Inferring the global phylodynamics of influenza A/H3N2 viruses in Taiwan

Conclusion We comprehensively investigated the evolutionary history of Taiwanese strains in 1979–2017. An epidemic caution could thus be raised if genetic diversity was found to have peaked. An example showed a newly-discovered cluster in 2016–2017 strains featuring a mutation N31S together with HA-160 quasispecies. Phylogeographic analysis, moreover, provided useful insights in tracing the possible source and migrations of these epidemics around the world. We demonstrated that Asian destinations including Taiwan were the immediate followers, while U.S. continent was predicted the origin of two summer epidemics in 2007 and 2009.
Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research