Differential expression of various clones of estrogen receptor in cell block preparation of lung adenocarcinoma
ConclusionsA small subset of pulmonary adenocarcinomas shows immunoreactivity for ER clones 6F11 and 1D5 in FNA samples (18.2% and 9.1%, respectively). The absence of immunoreactivity for ER‐SP1 clone indicates higher specificity of this clone in non‐breast tissue. The differential diagnostic value of all ER clones in malignant PEs appears to be secure. Larger studies are necessary to validate this observation.
Source: Diagnostic Cytopathology - Category: Pathology Authors: Laleh Hakima, Kathie Schlesinger, Jaya Sunkara, Rouzan G. Karabakhtsian Tags: ORIGINAL ARTICLE Source Type: research
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