CONCLUSION: The re-evaluation of the clinically-designated positive Ara h 2-sIgE cut-off value revealed that the cut-off value was appropriate. The differential diagnosis of tree nut allergies was suggested to be important in PA patients. PMID: 29459524 [PubMed - in process]
Source: Allergology International - Category: Allergy & Immunology Tags: Arerugi Source Type: research

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Jared Huston, MD, a trauma surgeon at Northwell Health on New York's Long Island, spoke straight to the point about the current state of treatment for hemorrhagic shock. While traumatic wounds to extremities can be treated with a tourniquet, such wounds suffered internally are often fatal unless the patient can be transported quickly to an operating room. "There are no efficacious approaches to treating noncompressible hemorrhage," Huston said. "That's really the problem. If you're injured intra-abdominally or in the chest, and you're not brought somewhere where a trauma surgeon can operate on you and stop t...
Source: MDDI - Category: Medical Devices Authors: Tags: Electronics Source Type: news
In this study, recombinant crayfish MLC1 (rMLC1) was expressed and confirmed by mass spectrometry. Circular dichroic analysis and serological test were performed for the measuring of structural and immunological properties of rMLC1. Specific-protein-A-enriched IgG raised in rabbits against purified rMLC1 was used to screen a phage display random peptide library. Nine MLC1 mimotope clones were identified among 16 random clones after biopanning. Five conformational epitopes were identified with the program LocaPep, and mapped into 3 epitope regions at the antibody-binding interface of MLC1. MLC1 of crayfish showed high prima...
Source: Food Chemistry - Category: Food Science Source Type: research
The meeting brings together MS experts, practitioners, and trainees alike for 3 days of learning and networking.Medscape Medical News
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Neurology & Neurosurgery News Source Type: news
T cells provide essential immunosurveillance to combat and eliminate infection from pathogens, yet these cells can also induce unwanted immune responses via T cell receptor (TCR) cross-reactivity, also known as heterologous immunity. Indeed, pathogen-induced TCR cross-reactivity has shown to be a common, robust, and functionally potent mechanism that can trigger a spectrum of human immunopathologies associated with either transplant rejection, drug allergy, and autoimmunity. Here, we report that several virus-specific CD8+ T cells directed against peptides derived from chronic viruses (EBV, CMV, and HIV-1) presented by hig...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
ConclusionEczema phenotypes were differentially associated with risks of respiratory and allergic conditions in school-aged children. Children with early transient and persistent eczema might benefit from more intense follow-up for early identification and treatment of asthma and allergies.
Source: Clinical and Translational Allergy - Category: Allergy & Immunology Source Type: research
The President has proposed a $38.7 billion budget for the National Institutes of Health in fiscal year (FY) 2021. This translates to a $3 billion or 7 percent cut in the agency’s funding compared to FY 2020. The NIH budget request includes a $50 million initiative to use artificial intelligence (AI) to develop a better understanding of the causes of chronic diseases and to identify early treatments. This plan is in line with the Administration’s “Industries of the Future” effort, which supports using and developing AI across sectors. The budget would provide $50 million for the Childhood Cancer ...
Source: Public Policy Reports - Category: Biology Authors: Source Type: news
Pediatric myelin oligodendrocyte glycoprotein (MOG)-antibody-associated syndromes should be expanded beyond demyelinating syndromes to include encephalitis, according to a multicenter study.Reuters Health Information
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Neurology & Neurosurgery News Source Type: news
Infants in homes with frequent cleaning product use have increased odds for childhood wheeze, asthma
Source: Pulmonary Medicine News - Doctors Lounge - Category: Respiratory Medicine Tags: Family Medicine, Pediatrics, Pulmonology, Allergy, Journal, Source Type: news
Condition:   Healthy Volunteers Interventions:   Drug: AV-1;   Drug: Placebo Sponsors:   AbViro LLC;   National Institute of Allergy and Infectious Diseases (NIAID) Recruiting
Source: - Category: Research Source Type: clinical trials
Publication date: Available online 17 February 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): James H. Clark, Fuad M. Baroody, Robert M. NaclerioAbstractSinonasal disease in its multiple forms affects billions of people worldwide. Although physicians train to precisely diagnose a patient and then treat appropriately, the sheer number of people afflicted with sinonasal disease precludes this approach. We argue that patients should first be treated with an intranasal corticosteroid for 2 weeks. Based on their perceived response, they should be triaged. Those who respond well can be instruct...
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
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