Expression of MAGE ‐A and NY‐ESO‐1 cancer‐testis antigens is enriched in triple‐negative invasive breast cancers

ConclusionsMAGE‐A and NY‐ESO‐1 are frequently expressed in TNBC (~47% and 17% of TN cases, respectively), suggesting that targeting them could be feasible in this patient group. Expression is reasonably homogeneous in positive cases suggesting that IHC analysis of tissue biopsies would be a reliable companion biomarker.This article is protected by copyright. All rights reserved.

Source: Histopathology - February 21, 2018 Category: Pathology Authors: Ashwini Raghavendra, Priyakshi Kalita ‐de Croft, Ana Cristina Vargas, Chanel E. Smart, Peter T. Simpson, Jodi M. Saunus, Sunil R. Lakhani Tags: Original Article Source Type: research