Computational Investigation of a Self-Powered Fontan Circulation

We report preliminary results of an analysis of this circulation using a tightly-coupled, multi-scale computational fluid dynamics model. Our calculations show that, constraining the excess volume load to the ventricle at 50% (pulmonary to systemic flow ratio of 1.5), an optimally configured IJS can lower venous pressure by 3 mmHg while increasing systemic oxygen delivery. Even this small decrease in venous pressure may have substantial clinical impact on the Fontan patient. These findings support the potential for a straightforw ard surgical modification to decrease venous pressure, and perhaps improve clinical outcome in selected patients.
Source: Cardiovascular Engineering and Technology - Category: Cardiology Source Type: research