'Icebreaker' protein opens genome for t cell development, Penn researchers find

(University of Pennsylvania School of Medicine) Researchers describe the role of a transcription factor called TCF-1 in targeting the condensed chromatin and regulating the availability of genome sequences in T-cell development. The new connection between TCF-1 and chromatin will aid in developing new therapies using epigenetic drugs to alter T-cell fate in cancer, autoimmune disorders, and infectious diseases.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news