Paracetamol linked to depletion of sulphated sex hormones
The use of paracetamol during pregnancy has been associated with sex hormone depletion, which may lead to urogenital malformation in males, a study inEBioMedicine suggests.Medscape
Authors: Capuano V, Srour M, Miere A, Guenoun S, Astroz P, Semoun O, Souied EH, Querques G PMID: 30442488 [PubMed - as supplied by publisher]
This article presents the 2018 status of policy guidance for the use of pre-exposure prophylaxis (PrEP) during peri-conception, pregnancy and breastfeeding, particularly looking at countries with high HIV prevalence, including those in sub-Saharan Africa. Pregnancy was often recognized as a period with elevated HIV risk but few PrEP guidance documents have a recommendation specific to PrEP use among pregnant women. As PrEP implementation becomes more widespread across the globe, countries can include guidance for women during peri-conception, pregnancy, and breastfeeding.
Even though there are still a lot of unknowns about the effects of marijuana exposure in the womb and from breast milk, research to date still suggests that pregnant and nursing women avoid cannabis, U.S. doctors recommend.Reuters Health Information
Authors: Rosenblat JD, Simon GE, Sachs GS, Deetz I, Doederlein A, DePeralta D, Dean MM, McIntyre RS Abstract Objective: To identify patient-reported factors that influence medication treatment decisions among individuals with bipolar and unipolar depression. Methods: The Depression and Bipolar Support Alliance (DBSA) conducted an online survey February 2016 to April 2016 asking participants about factors that influence treatment decisions (eg, starting and stopping specific medications). Results: In total, 896 participants completed the survey (49.9% unipolar depression [n = 447] and 50.1% bipolar depressio...
Publication date: Available online 17 November 2018Source: Pharmacological ResearchAuthor(s): Lesley Brennan, Styliani Goulopoulou, Stephane L. BourqueAbstractCardiovascular diseases (CVD) are a leading cause of mortality worldwide. Despite recognizing the importance of risk factors in dictating CVD susceptibility and onset, patient treatment remains a challenging endeavor. Increasingly, the benefits of prevention and mitigation of risk factors earlier in life are being acknowledged. The developmental origins of health and disease posits that insults during specific periods of development can influence long-term health out...
ConclusionsTreatment with warfarin or aspirin both lead to similar outcomes after surgical bAVR. Combining aspirin with warfarin may lead to a small decrease in thromboembolism and mortality but is accompanied by increased bleeding. For TAVR patients, aspirin is equivalent to DAPT for reducing thromboembolism and mortality, with a possible decrease in bleeding.
(Natural News) Clinical trials have shown an association between the autism spectrum disorder (ASD) and maternal immune activation (MIA), an active immune response after an infectious exposure during pregnancy, but this study is the first one to examine its link to an increase in behavioral abnormalities in children. The connection between ASD and MIA is...
ConclusionsResults suggest that the nicotine patch incentives motivated women to call the Helpline, even pregnant women who needed a physician's approval consistent with current American College of Obstetricians and Gynecologists cautions about the appropriateness of the patch during pregnancy.Supplement informationThis article is part of a supplement entitled Advancing Smoking Cessation in California's Medicaid Population, which is sponsored by the California Department of Public Health.
CONCLUSION: The aim of this review, other than providing a summarized update on the clinical knowledge on this special topic, is also to raise awareness for the need to conduct larger systematic studies in order to adequately evaluate the use of biologics in these special patient categories and therefore draw definite conclusions on their safety profile. PMID: 30428753 [PubMed - as supplied by publisher]
ConclusionsThe iHealth Track and Omron HEM-9210T automated blood pressure monitors are validated for use in pregnancy. These two devices can now be added to the short list of validated devices in pregnancy and can be used for self-measurement of blood pressure in a telemonitoring setting of pregnant patients with (a high risk of) hypertensive disease.