ISSLS PRIZE IN CLINICAL SCIENCE 2018: longitudinal analysis of inflammatory, psychological, and sleep-related factors following an acute low back pain episode —the good, the bad, and the ugly

ConclusionsThis is the first evidence of a relationship between an “acute-phase” systemic inflammatory response and recovery at 6 months. High inflammation (CRP/IL-6) was associated with good recovery, but specific elevation of TNF, along with depressive symptoms, was associated with bad recovery. Depression and TNF may have a two-way relationship.Graphical abstractThese slides can be retrieved under Electronic Supplementary Material.

Source: European Spine Journal - February 19, 2018 Category: Orthopaedics Source Type: research