Neurotrophin-3 restores synaptic plasticity in the striatum of a mouse model of Huntington's disease.
CONCLUSION: NT-3 modulates corticostriatal transmission through TrkB stimulation and restores striatal LTD by signaling through its TrkC receptor.
PMID: 29453932 [PubMed - as supplied by publisher]
Source: CNS Neuroscience and Therapeutics - Category: Neuroscience Authors: Gómez-Pineda VG, Torres-Cruz FM, Vivar-Cortés CI, Hernández-Echeagaray E Tags: CNS Neurosci Ther Source Type: research
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