Risk factors influencing outcome of acute leukemia patients relapsing after allogeneic hematopoietic stem cell transplantation

Identifying risk factors influencing post-HSCT relapse outcome in acute leukemia is essential. 43 patients were studied. Older age and failure to achieve CR following treatment were associated with inferior OS. Female sex, extramedullary relapse and absence of post-relapse GVHD were associated with lower CR. Absence of extramedullary relapse, treatment with DLI and occurrence of post-relapse GVHD were associated with higher NRM.

Source: Clinical Lymphoma, Myeloma and Leukemia - February 17, 2018 Category: Hematology Authors: Amro M.S. El-Ghammaz, Mostafa K. El-Razzaz Tags: Original Study Source Type: research