The 2018 Flu Season Might Finally Be Leveling Off

(NEW YORK) — This nasty flu season, which has been worsening for months, may finally be leveling off. Health officials on Friday said about 1 of every 13 visits to the doctor last week was for fever, cough and other symptoms of the flu. That’s no reason for health officials to celebrate yet: That level is among the highest in a decade. But it’s no worse than last week, and flu activity had been increasing each week since November. The Centers for Disease Control and Prevention report said the number of states reporting heavy flu patient traffic also held steady at 43. “I thought I was going to die, I really did,” said Ben Bland, a 39-year-old event planner in Kansas City, Missouri, who was hospitalized this week with pneumonia on top of flu. “My lungs felt like they were going to blow out of my esophagus every time I coughed. My body ached head to toe.” This season started early and has been driven by a formidable type of flu that tends to put more people in the hospital and cause more deaths. Making a bad year worse, this year’s flu vaccine is estimated to be only 25 percent effective against that type. Preliminary data released last week indicated patient traffic in doctor’s offices and emergency rooms this flu season was as bad as the height of the swine flu pandemic in 2009. However, the CDC readjusted its numbers down slightly in Friday’s report, meaning this season did not quite match the intensity of flu acti...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized APH flu healthytime onetime Source Type: news

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We describe the case of a 75-year-old patient with late-onset schizophrenia who used clozapine. During a hospital admission due to pneumonia, she developed a form of acute dystonia consisting of a rotational torticollis, which disappeared rapidly after treatment with biperiden. Blood examination showed an increase of the clozapine level, probably due to the infection. This case report shows that acute dystonia, although very rare, can occur during treatment with clozapine; therefore awareness is needed of the circumstances that can alter clozapine levels. PMID: 30536298 [PubMed - in process]
Source: Tijdschrift voor Psychiatrie - Category: Psychiatry Authors: Tags: Tijdschr Psychiatr Source Type: research
The interferons (IFNs) are a primary defense against pathogens because of the strong antiviral activities they induce. IFNs can be classified into three groups: type I, type II and type III, according to their genetic, structural, and functional characteristics and their receptors on the cell surface. The type I IFNs are the largest group and include IFN- α, IFN-β, IFN-ε, IFN-ω, IFN-κ, IFN-δ, IFN-τ and IFN-ζ. The use of IFNs for the treatment of viral infectious diseases on their antiviral activity may become an important therapeutic option, for example, IFN-α is well kno...
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research
This study analyzes quality traits of longissimus lumborum and gluteus medius in surgically castrated (SC) males, inmunocastrated (IC) males and IC female Iberian pigs reared in intensive conditions (n = 18/sex). Vaccination with Improvac® was applied at 18 and 26 weeks of age and slaughtering at 31 weeks. At such conditions, notable sex differences were found. Both muscles of IC males were less red (P 
Source: Meat Science - Category: Food Science Source Type: research
This study evaluated different gilt vaccination protocols against Mycoplasma (M.) hyopneumoniae at acclimation and their effect on the genetic diversity. A total of 180 M. hyopneumoniae naïve gilts were selected 1 week post-entry (wpe) at the acclimation barn in a clinically affected M. hyopneumoniae farm. Gilts were distributed according to the M. hyopneumoniae antibodies levels into three different vaccination schedules: A) four doses of a M. hyopneumoniae commercial vaccine at 2, 4, 6 and 8 wpe; B) two vaccine doses at 2 and 6 wpe and PBS at 4 and 8 wpe; and C) four PBS doses at the same wpe. Detection of M. hyopne...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
Publication date: Available online 13 December 2018Source: Molecular Aspects of MedicineAuthor(s): Aitak Farzi, Ahmed M. Hassan, Geraldine Zenz, Peter HolzerAbstractThe global prevalence of diabesity is on the rise, and the clinical, social and economic health burden arising from this epidemic is aggravated by a significant co-morbidity of diabesity with neuropsychiatric disease, particularly depression. Importantly, not only is the prevalence of mood disorders elevated in patients with type 2 diabetes, depressed patients are also more prone to develop diabetes. This reciprocal relationship calls for a molecular and system...
Source: Molecular Aspects of Medicine - Category: Molecular Biology Source Type: research
Publication date: March 2019Source: Fish &Shellfish Immunology, Volume 86Author(s): Saekil Yun, Jin Woo Jun, Sib Sankar Giri, Hyoun Joong Kim, Cheng Chi, Sang Geun Kim, Sang Wha Kim, Jung Woo Kang, Se Jin Han, Jun Kwon, Woo Taek Oh, Se Chang ParkAbstractOver the last 50 years, various approaches have been established for the development of antigens for immunostimulation. We used phage lysate (PL), composed of inactivated antigens by the lytic bacteriophage pAh 6-c for Aeromonas hydrophila JUNAH strain to develop a vaccine for the prevention of A. hydrophila infection in Cyprinus carpio (common carp). We also assessed t...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
Publication date: 1 March 2019Source: Carbohydrate Polymers, Volume 207Author(s): Alžbeta Čížová, Katarína Csomorová, Jozef Rychlý, Slavomír BystrickýAbstractInfection with Candida albicans can prove lethal in immuno-compromised patients. It is imperative to develop a vaccine against this common organism. The amphoteric derivatives of the mannan component of the Candida cell wall may present a prospective target for the development of such a vaccine; however, the radical processing by antigen-presenting cells of the immune system is not fully understood. In this work a se...
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
Publication date: Available online 12 December 2018Source: The Lancet Respiratory MedicineAuthor(s): Sheena G Sullivan, Benjamin J Cowling
Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research
Publication date: Available online 12 December 2018Source: The Lancet Respiratory MedicineAuthor(s): Christopher E Troeger, Brigette F. Blacker, Ibrahim A. Khalil, Stephanie R M Zimsen, Samuel B. Albertson, Degu Abate, Jemal Abdela, Tara Ballav Adhikari, Sargis Aghasi Aghayan, Sutapa Agrawal, Alireza Ahmadi, Amani Nidhal Aichour, Ibtihel Aichour, Miloud Taki Eddine Aichour, Ayman Al-Eyadhy, Rajaa M Al-Raddadi, Fares Alahdab, Kefyalew Addis Alene, Syed Mohamed Aljunid, Nelson Alvis-GuzmanSummaryBackgroundAlthough the burden of influenza is often discussed in the context of historical pandemics and the threat of future pande...
Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research
Publication date: Available online 12 December 2018Source: Respiratory InvestigationAuthor(s): Yuta Kono, Masako To, Ryuta Tsuzuki, Kosuke Haruki, Yasuo To
Source: Respiratory Investigation - Category: Respiratory Medicine Source Type: research
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