Impact of Formulation Excipients on the Thermal, Mechanical, and Electrokinetic Properties of Hydroxypropyl methylcellulose acetate succinate (HPMCAS)

This study facilitated the understanding of the HPMCAS aggregation mechanism, in addition to identifying suitable stabilizing agents. These stabilizing excipients could potentially be used to develop a stable aqueous coating formulation that does not exhibit polymer aggregation and nozzle clogging during the coating process. Graphical abstract
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research