CDC Estimates This Year ’s Flu Vaccine Is Only 36 Percent Effective

Early estimates suggest the flu shot only worked about a third of the time this year. Between Nov. 2 and Feb. 3, total vaccine effectiveness was estimated at 36%, according to a report released Thursday by the CDC. When broken down by strain, however, efficacy varied widely. H3N2, the dominant strain circulating this flu season, is notoriously more virulent and less receptive to vaccination than other types of influenza. True to form, vaccine effectiveness against this strain was low this year — approximately 25%, according to the CDC report. (That’s actually better than experts originally feared, based on trends from Canada and Australia, where the flu vaccine was only about 10% effective.) By contrast, the report says the shot worked an estimated 67% of the time against the less-severe H1N1 and 42% of the time against influenza B viruses. The shot’s efficacy also depends on a person’s age. Among children between the ages of six months and eight years, for example, the shot reduced the risk of H3N2 illness by 59%, according to the report. 36% effectiveness may not seem very impressive, but the CDC emphasizes in the report that even small increases in immunity can have a large impact on public health. CDC data has shown that even in 2014-2015, a year when vaccine effectiveness didn’t even hit 20%, immunizations prevented as many as 144,000 flu-related hospitalizations and 4,000 deaths. Plus, people who get the shot, but who still end up getting...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthytime onetime public health Source Type: news

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Conclusions: Human challenge studies and systems biology approaches are important tools that should be used in concert to advance our understanding of influenza infection and provide targets for novel therapeutics and immunizations. Introduction Although influenza virus was recognized as an important pathogen over a century ago, influenza continues to cause a significant burden of disease. In the United States alone, it's estimated that in the 2017–2018 season there were 959,000 hospitalizations related to influenza illness, and 79,400 deaths (CDC, 2018). Worldwide, WHO estimates that annual influenza...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
The Objective: To assess the seasonal incidence rate (IR) and mortality rate (MR) because of acute respiratory viral infections (ARVI) and pneumonia (P) in the population of Moscow.The Methods: We used the data on IR and MR of the population because of infectious and parasitic diseases (IPD) (A00-V99 ICD-10), ARVI (J00-02.8-9; J03-J06; J20-J22 ICD-10), P (J12-J16, J18 MCD-10) of the official statistical forms 1, 2, 5, medical death certificates (MDC) of patients from hospitals, microbiology assays nasopharyngeal swabs identifying RNA of influenza virus A(H1N1)09, A(H3N2) and B; bacteriological examinations of sputum.Result...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Epidemiology Source Type: research
Conclusions: Often manifested as lower respiratory tract infection, influenza may cause epidemics with increased mortality rate. Influenza should be suspected when interstitial pattern was seen on radiological images. H1N1 cases course worse. Since the prognosis is better in vaccinated patients, seasonal influenza vaccination among the community needs to be elevated. In addition, protective measures like vaccination should be taken in pregnancy to avoid preterm delivery or abortion. PMID: 30246658 [PubMed - in process]
Source: Tuberkuloz ve Toraks - Category: Respiratory Medicine Authors: Tags: Tuberk Toraks Source Type: research
Early estimates suggest the flu shot only worked about a third of the time this year. Between Nov. 2 and Feb. 3, total vaccine effectiveness was estimated at 36%, according to a report released Thursday by the CDC. When broken down by strain, however, efficacy varied widely. H3N2, the dominant strain circulating this flu season, is notoriously more virulent and less receptive to vaccination than other types of influenza. True to form, vaccine effectiveness against this strain was low this year — approximately 25%, according to the CDC report. (That’s actually better than experts originally feared, based on tren...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthytime onetime public health Source Type: news
Conclusions: Development of severe complications of influenza has been associated with the lack of immunization, early diagnosis, timely antiviral therapy and late medical aid appealability. The timely inclusion of ECMO to the therapeutic regimen allows to treat severe hypoxemia, which is not corrected by other methods, and this increases the chances of patients’ recovery.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Acute Critical Care Source Type: research
In conclusion, influenza A virus infection was detected rather high with a rate of 20.5% in the study group. The monitoring of influenza virus types and subtypes is required for the evaluation of influenza vaccine strains and circulating influenza viruses and for the identification of subtypes with pandemic potential. Planning for appropriate antiviral therapy using real-time RT-PCR in the early diagnosis of influenza virus infections will significantly contribute to the management of the patient's treatment. Thus, unnecessary drug use will be prevented and controlled with effective treatment of the disease at the time of ...
Source: Mikrobiyoloji Bulteni - Category: Microbiology Tags: Mikrobiyol Bul Source Type: research
Conclusion In the patients who developed influenza virus-associated pneumonia, those with pH1N1 virus-associated pneumonia frequently developed primary viral pneumonia resulting in bilateral and broad areas of GGOs on imaging, whereas patients with H3N2 virus-associated pneumonia frequently showed consolidation and diffuse bronchial wall thickening on pulmonary imaging. PMID: 27041156 [PubMed - in process]
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
Conclusion Understanding epidemiology of HCoV-NL63 in Taiwan provides an insight for worldwide surveillance of HCoV-NL63 infection.
Source: Journal of Microbiology, Immunology and Infection - Category: Microbiology Source Type: research
Last year was a lousy year for the flu vaccine. Hospitalizations for flu hit a nine-year high, and the vaccine prevented flu in only 23% of all recipients, compared with 50% to 60% of recipients in prior years. Why does the flu vaccine work well in some winters and not others? The flu vaccine primes the immune system to attack two proteins on the surface of the influenza A virus, hemagglutinin (H) and neuraminidase (N). Different flu strains have different combinations of these proteins — for example, the strains targeted by recent flu vaccines are H3N2 and H1N1. Unfortunately, the influenza virus is microbiology&rsq...
Source: New Harvard Health Information - Category: Consumer Health News Authors: Tags: Cold and Flu Vaccines Flu Shot flu vaccine Source Type: news
Conclusion: The antibody response to 2009 pandemic influenza virus was widespread in convalescence samples from patients with confirmed pandemic influenza infection but the GMT was below the protective titre. There was no evidence that antibodies to the swine influenza viruses had cross-protective effect against the 2009 pandemic influenza virus.
Source: The Journal of Infection in Developing Countries - Category: Infectious Diseases Source Type: research
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