MECHANISMS IN ENDOCRINOLOGY: Diabetic Cardiomyopathy - Pathophysiology and Potential Metabolic Interventions.

MECHANISMS IN ENDOCRINOLOGY: Diabetic Cardiomyopathy - Pathophysiology and Potential Metabolic Interventions. Eur J Endocrinol. 2018 Feb 12;: Authors: Levelt E, Gulsin GS, Neubauer S, McCann GP Abstract Heart failure is a major cause of morbidity and mortality in type 2 diabetes. Type 2 diabetes contributes to the development of heart failure through a variety of mechanisms, including disease specific myocardial structural, functional and metabolic changes. This review will focus on the contemporary contributions of state of the art non-invasive technologies to our understanding of diabetic cardiomyopathy, including data on cardiac disease phenotype, cardiac energy metabolism and energetic deficiency, ectopic and visceral adiposity, diabetic liver disease, metabolic modulation strategies, and cardiovascular outcomes with new classes of glucose lowering therapies. PMID: 29440374 [PubMed - as supplied by publisher]
Source: European Journal of Endocrinology - Category: Endocrinology Authors: Tags: Eur J Endocrinol Source Type: research