Cannabis for vismodegib-related muscle cramps in a patient with advanced basal cell carcinoma

Vismodegib is a hedgehog inhibitor drug indicated for metastatic or locally advanced basal cell carcinoma (BCC) that is not fit for surgery or radiation therapy. One of the most common side effects of vismodegib is muscle cramps which can cause a decrease in quality of life (QoL) and treatment discontinuation. Cannabis is known to improve spasticity (including muscle cramps) in multiple sclerosis patients [1].
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research