Epididymo-orchitis caused by enteric organisms in men & gt;  35 years old: beyond fluoroquinolones

AbstractEpididymo-orchitis is a common urological condition in men of all ages, causing a unilateral or bilateral swelling of the epididymis and/or testis. It is frequently caused by sexually transmitted infections,Chlamydia trachomatis andNeisseria gonorrheae, as well as common enteric organisms implicated in urinary tract infections. Men over 35  years old may develop epididymo-orchitis associated with enteric organisms, often associated with functional bladder outlet problems such as benign prostatic hyperplasia or urethral stricture disease. Fluoroquinolones, especially ciprofloxacin, have long been the mainstay of treatment for these in fections; however, rising resistance to ciprofloxacin inE.coli isolates in Europe and the USA means that there is an unprecedented necessity for alternative antimicrobials with adequate penetration into genital tissues (epididymis and testes) to allow appropriate and comprehensive treatment of epididymo-orchitis in this group of patients.
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research