Evaluation of indications for reduced-dose NOACs in hospitalized atrial fibrillation patients.

CONCLUSIONS: Standard doses of NOACs were prescribed to most hospitalized AF patients. Apixaban was prescribed more frequently in the reduced dose regimen while the frequencies of standard and reduced doses being prescribed were similar for dabigatran and rivaroxaban alike. Absence of indications for dose reduction as defined in relevant guidelines and Summaries of Product Characteristics was identified in 16% of patients receiving reduced doses of NOACs. More than one indication for dose reduction was identified in most patients receiving reduced-dose dabigatran while one dose reduction was identified in most patients receiving reduced-dose rivaroxaban. PMID: 29441513 [PubMed - as supplied by publisher]
Source: Polish Heart Journal - Category: Cardiology Authors: Tags: Kardiol Pol Source Type: research