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Asthma medication linked to infertility in women

(University of Adelaide) Women with asthma who only use short-acting asthma relievers take longer to become pregnant than other women, according to international research led by the University of Adelaide.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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In conclusion, these data suggest that increased prenatal Ang2 has a predominant impact on the properties of renal Na,K-ATPase in both sexes. Moreover, the enzyme is resistant to higher salt intake in offspring prenatally exposed to Ang2. PMID: 29769424 [PubMed - in process]
Source: Journal of Physiology and Pharmacology - Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research
Authors: Iciek R, Brazert M, Wender-Ozegowska E, Pietryga M, Brazert J Abstract Type 1 diabetes mellitus (T1DM) is still related to altered fetal growth and severe maternal complications. We studied the possible role of placental visfatin/nicotinamide phosphoribosyltransferase (NAMPT) in fetal development in T1DM pregnancies, the possible role of placental visfatin in fetal macrosomia. Sixty five pregnant women with T1DM and singleton pregnancy were qualified into the study. Placental visfatin expression was by analysed by RT-PCR. We demonstrated the lowest expression of placental visfatin in women who delivered ne...
Source: Journal of Physiology and Pharmacology - Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research
CONCLUSIONS: The most prevalent diagnosis in children with BD-resistant airflow limitation is asthma. Allergic rhinitis and premature birth are common co-morbidities. Children without a history of asthma, as well as those with asthma but no allergic rhinitis, had lower pulmonary function. Children with BD-resistant airflow limitation may represent a sub-group of children with persistent obstruction and high risk for life-long airway disease. PMID: 29771599 [PubMed - as supplied by publisher]
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
CONCLUSIONS: There was general agreement between asthma diagnoses reported in the NHIS when compared to medical claims. Discordance was greatest among children with co-occurring conditions. PMID: 29771597 [PubMed - as supplied by publisher]
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
In this study, we investigated the mechanistic basis for improvement of semen parameters and reversal of testis damage by QLPs in a rat model of oligoasthenospermia induced by treatment with tripterygium glycosides (TGs) (40 mg/kg) once daily for 4 weeks. Rats were administered QLPs (1.62 g/kg or 3.24 g/kg) each day for 60 days, with untreated animals serving as controls. The concentration and motility of sperm extracted from rat epididymis were determined, whereas histopathological examination and immunohistochemical apoptosis analysis of rat testes was performed. Expression profiles of apoptosis-related genes were determ...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
The Texas Medical Association (TMA) will not rest until maternal mortality is eliminated in Texas. Carlos J. Cardenas, MD, TMA ’s immediate past president, threw down a gauntlet today to his physician colleagues — a goal of zero deaths among Texas women who are pregnant or new mothers.
Source: TMA News Room - Category: Consumer Health News Source Type: news
Researchers from the University of Adelaide found female sufferers who take preventer inhalers, which contain steroids, have the same pregnancy prospects as non-asthma patients.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Background: Asthma has been linked with prolonged time to pregnancy, but our knowledge of asthma and infertility is limitedObjective: To explore a possible association between asthma and infertilityMethods: All pregnant women referred to Hvidovre Hospital (HVH) have been offered enrolment into the Management of Asthma during Pregnancy (MAP) program since 2007. Pregnant women were eligible for the present study provided they had a diagnosis of asthma and had their first visit to the respiratory outpatient clinic within the first 18 weeks of pregnancy (cases). Controls were the three consecutive women giving birth at HVH. In...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Clinical Problems Asthma Source Type: research
Environmental exposures are becoming increasingly recognized as important contributors to health. Over the last decade, a significant number of studies have examined the relationship between ambient air and traffic-related air pollution and the incidence of asthma, cardiovascular disease, and reproductive outcomes. Proximity to major roadways has recently been shown to impact time to pregnancy and infertility rates.1 We sought to determine if residential proximity to in-state major U.S. highways and interstates impacts IVF outcomes.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Poster session Source Type: research
Conclusion: To address the many challenges posed by EDCs, we argue that Africans should take the lead in prioritization and evaluation of environmental hazards, including EDCs. We recommend the institution of education and training programs for chemical users, adoption of the precautionary principle, establishment of biomonitoring programs, and funding of community-based epidemiology and wildlife research programs led and funded by African institutes and private companies. https://doi.org/10.1289/EHP1774 Received: 16 February 2017 Revised: 22 May 2017 Accepted: 24 May 2017 Published: 22 August 2017 Address correspond...
Source: EHP Research - Category: Environmental Health Authors: Tags: Commentary Source Type: research
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