Promotion of Sema4D expression by tumor-associated macrophages: Significance in gastric carcinoma.

CONCLUSION: TAMs promote the invasion and metastasis of gastric carcinoma cells possibly through upregulated secretory Sema4D protein expression. Combined detection of TAM markers, CD68 and Sema4D, in gastric carcinoma tissue shows potential to predict the trend of gastric carcinoma progression.
PMID: 29434448 [PubMed - in process]

Source: World Journal of Gastroenterology : WJG - February 7, 2018 Category: Gastroenterology Authors: Li H, Wang JS, Mu LJ, Shan KS, Li LP, Zhou YB Tags: World J Gastroenterol Source Type: research