SMURF1 facilitates estrogen receptor ɑ signaling in breast cancer cells.

CONCLUSIONS: Our study reveals a novel positive feedback between SMURF1 and ER alpha signaling in supporting breast cancer growth. Targeting SMURF1 could be one promising strategy for ER alpha positive breast cancer treatment.
PMID: 29433542 [PubMed - in process]

Source: Clinical Genitourinary Cancer - February 12, 2018 Category: Cancer & Oncology Authors: Yang H, Yu N, Xu J, Ding X, Deng W, Wu G, Li X, Hou Y, Liu Z, Zhao Y, Xue M, Yu S, Wang B, Li X, Niu G, Wang H, Zhu J, Zhuang T Tags: J Exp Clin Cancer Res Source Type: research