Allergic and nonallergic asthma in children: are they distinct phenotypes?

Allergic and nonallergic asthma in children: are they distinct phenotypes?
Iran J Allergy Asthma Immunol. 2014 Oct;13(5):370-4
Authors: Mahdaviani SA, Mohajerani SA, Fakhri M, Ebrahimi M, Bashardoost B, Razavi SJ, Toolabi M, Tajik A, Khalilzadeh S, Masjedi MR
Abstract
The aim of current study is to describe clinical similarities and differences between atopic and non-atopic asthma in children. In a cross-sectional study, 95 asthmatic children (75 allergics and 20 nonallergics) were included in the study. Demographic, clinical, and familial history were compared between two groups. There was no significant differences between variables like sex, age of onset (p=0.75), severity (p=0.70), and family history among the two groups (p=0.42). Patients with allergic asthma were significantly older than those with non- allergic asthma (11.28±3.19 and 9.75±2.35 years, respectively, p=0.02). The controversy lingers over the presence of a completely distinct phenotype of non-atopic asthma in children. Our study suggested that phenotypes of allergic and non-allergic asthma in children were not entirely distinct.
PMID: 25150079 [PubMed - in process]

Source: Iranian Journal of Allergy, Asthma and Immunology - August 31, 2014 Category: Allergy & Immunology Authors: Mahdaviani SA, Mohajerani SA, Fakhri M, Ebrahimi M, Bashardoost B, Razavi SJ, Toolabi M, Tajik A, Khalilzadeh S, Masjedi MR Tags: Iran J Allergy Asthma Immunol Source Type: research