Asbestos (Exposure Dangers, Testing, Symptoms)
Title: Asbestos (Exposure Dangers, Testing, Symptoms)Category: Diseases and ConditionsCreated: 2/21/2000 12:00:00 AMLast Editorial Review: 2/12/2018 12:00:00 AM
AbstractPrimary malignant pericardial mesothelioma (PMPM) is an extremely rare tumor, which may appear as a localized or a diffuse mass encasing the heart. Diffuse PMPMs have a poor prognosis due to the difficulty of surgical excision, whereas localized PMPMs have clear margins, thus facilitating surgical excision. Timely diagnosis and proper treatment are crucial for a favorable prognosis. Eight cases of localized PMPMs have been reported so far, but their characteristics have not been fully described. Herein, we present a patient with localized PMPM and describe the diagnosis methods, treatment, and outcomes of these tumors.
AbstractComplete resection is the mainstay of treatment for thymoma. Even for advanced-stage thymoma with pleural dissemination, complete resection with extrapleural pneumonectomy may provide a favorable prognosis. Pleurectomy decortication, a lung-sparing surgery, has been preferably employed in recent years as an alternative surgical procedure for malignant pleural mesothelioma. However, little has been reported about pleurectomy decortication for other malignant tumors with pleural dissemination. Here, we present the first case of thymoma with pleural dissemination for which completeen bloc resection was achieved with e...
Decrease in Intracellular Perforin Levels and IFN-γ Production in Human CD8+ T Cell Line following Long-Term Exposure to Asbestos Fibers. J Immunol Res. 2018;2018:4391731 Authors: Kumagai-Takei N, Nishimura Y, Matsuzaki H, Lee S, Yoshitome K, Otsuki T Abstract Although the tumorigenicity of asbestos, which is thought to cause mesothelioma, has been clarified, its effect on antitumor immunity requires further investigation. We previously reported a decrease in the percentage of perforin+ cells of stimulated CD8+ lymphocytes derived from patients with malignant mesothelioma. Therefore, we examined ...
Publication date: December 2018Source: The Annals of Thoracic Surgery, Volume 106, Issue 6Author(s): Gregorio Laguna, Miriam Blanco, Gerardo Martínez, Yolanda Carrascal
A second South Carolina jury on Thursday failed to reach a verdict in the retrial of a case by a woman whose family said her long-term use of Johnson&Johnson's baby powder led to her death from asbestos-related cancer.
ConclusionConsidering the patient ’s occupational and environmental history, it is estimated that she had been exposed to asbestos significantly, so we determined that ovarian cancer in the patient is highly correlated with the occupational exposure of asbestos and environmental exposure is a possible cause as well. Social devices are needed to prevent further exposure to asbestos. It is also necessary to recognize that ovarian cancer can occur in workers who have previously been exposed to asbestos, and the education and social compensation for those workers are needed.
The objective of this study was to analyze the expression level and clinical role of soluble AXL (sAXL) in cancers affecting the serosal surfaces, with focus on ovarian carcinoma. METHODS: sAXL protein expression by ELISA was analyzed in 572 effusion supernatants, including 424 peritoneal, 147 pleural and 1 pericardial specimens. RESULTS: sAXL was overexpressed in peritoneal effusions compared to pleural and pericardial specimens (p
A California jury on Wednesday cleared Johnson&Johnson of liability in a case involving a woman who alleged that the company's talc-based products, including its baby powder, contain asbestos and caused her cancer, the company said.
Authors: Liu J, Liao X, Gu Y, Fu L, Zhao J, Li L, Chen Z, Jiang J PMID: 30416802 [PubMed]
All patients diagnosed with malignant mesothelioma should undergo genetic testing to better identify the most appropriate treatment plan, according to Dr. Michele Carbone, the director of thoracic oncology at the University of Hawaii Cancer Center. Genetic testing also could lead to a more accurate prognosis and help family members determine if they are more susceptible to the cancer. Carbone estimates only one-third of all mesothelioma patients today have undergone the testing. “Some of these patients could definitely benefit from genetic testing,” Carbone told The Mesothelioma Center at Asbestos.com. Carbon...