Asbestos (Exposure Dangers, Testing, Symptoms)

Title: Asbestos (Exposure Dangers, Testing, Symptoms)Category: Diseases and ConditionsCreated: 2/21/2000 12:00:00 AMLast Editorial Review: 2/12/2018 12:00:00 AM
Source: MedicineNet Lungs General - Category: Respiratory Medicine Source Type: news

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Abdominal ascites is most commonly caused by portal hypertension from liver cirrhosis. When present, portal hypertension is associated with an elevated serum-ascites albumin gradient (SAAG) ≥1.1 g/dL. In contrast, a SAAG #x3c; 1.1 g/dL suggests malignancy, tuberculosis, pancreatitis, or nephrotic syndrome. Here, we present a case of low SAAG ascites caused by epithelioid peritoneal mesothelioma in a woman with no known liver disease. The diagnosis proved elusive until diagnostic lapa roscopy with biopsy was performed.Case Rep Gastroenterol 2018;12:420 –424
Source: Case Reports in Gastroenterology - Category: Gastroenterology Source Type: research
We present two cases of DMM, one in a 47-year-old man and the other in a 64-year-old man. From detailed pathologic findings in these two cases, we conclude that cases of DMM that cannot otherwise be diagnosed with the use of conventional pleural biopsy, may be diagnosed successfully with the use of wedge lung resection.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Conditions:   B-cell Acute Lymphoblastic Leukemia;   Lymphoma;   Myeloid Leukemia;   Multiple Myeloma;   Hepatoma;   Gastric Cancer;   Pancreatic Cancer;   Mesothelioma;   Colorectal Cancer;   Esophagus Cancer;   Lung Cancer;   Glioma;   Melanoma;   Synovial Sarcoma;   Ovarian Cancer ;   Renal Carcinoma Intervention:   Biological: CAR-T cell immunotherapy Sponsors:   Shenzhen BinDeBio Ltd.;   The First Affiliated Hospital of Zhengzhou University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
The MD Anderson Cancer Center in Houston was named the No. 1 cancer care hospital in America by U.S. News &World Report for the fourth consecutive year. MD Anderson has been a leading specialty center for pleural mesothelioma treatment, which contributed to its top billing in the 2018-19 rankings. The center is in the recruiting or active-and-not recruiting stage for 15 different clinical trials involving mesothelioma. Memorial-Sloan Kettering Cancer Center in New York, the Mayo Clinic in Rochester, Minnesota, Dana-Farber and Brigham and Women’s Hospital in Boston, and the Cleveland Clinic, respectively, round o...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
Authors: Walter RFH, Werner R, Wessolly M, Mairinger E, Borchert S, Schmeller J, Kollmeier J, Mairinger T, Hager T, Bankfalvi A, Christoph DC, Eberhardt WEE, Plönes T, Aigner C, Schmid KW, Wohlschlaeger J, Mairinger FD Abstract Previously, our group demonstrated that nuclear expression of E3 ubiquitin ligase (MDM2) in malignant pleural mesothelioma (MPM) is significantly associated with decreased overall survival. A possible explanation may be that overexpression of MDM2 leads to a proteasomal degradation of TP53 that eventually results in a loss of TP53-induced apoptosis and senescence. It is well known from ...
Source: Journal of Oncology - Category: Cancer & Oncology Tags: J Oncol Source Type: research
Radiofrequency ablation (RFA) has been used successfully in Japan to treat post-surgery recurrence of malignant pleural mesothelioma, according to a case study published recently by the Society of Thoracic Surgeons. Although RFA has been utilized for several years to treat various thoracic lesions, the study authors believe this is the first time it worked effectively with mesothelioma cancer cells. “It shows promising efficacy,” the authors wrote. “Radiofrequency should be considered an option for treating recurrence of MPM [malignant pleural mesothelioma].” RFA is a minimally invasive medical proc...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news
Hypoxia is a hallmark of the solid tumor microenvironment and is associated with poor outcomes in cancer patients. The present study was performed to investigate mechanisms underlying the hypoxia-induced pheno...
Source: BMC Cancer - Category: Cancer & Oncology Authors: Tags: Research article Source Type: research
The PTEN-hamartoma-tumor-syndrome (PHTS) is caused by germline mutations in Phosphatase and Tensin homolog (PTEN) and predisposes to the development of several typical malignancies. Whereas PTEN mutations have be...
Source: BMC Medical Genetics - Category: Genetics & Stem Cells Authors: Tags: Case report Source Type: research
Publication date: Available online 13 August 2018Source: Materials LettersAuthor(s): A.I. Ruiz, A. Ortega, R. Fernández, J.F. Miranda, E. López Samaniego, J. CuevasAbstractThermochemical processes, using special clays as flux, have been developed for a complete mineralogical conversion of ACM waste into non-asbestos materials. This transformation manages to turn these wastes into a secondary raw materials reducing waste generation, principles in which is based on the Circular Economy.
Source: Materials Letters - Category: Materials Science Source Type: research
Clear cell variant of epithelioid mesothelioma is an extremely rare tumor with only isolated cases reported so far in the peritoneum. Here, we report a case of peritoneal epithelioid mesothelioma, clear cell variant, in a 63-year-old female patient with a novel VHL gene mutation and an unusual indolent clinical course. The patient, who has no clinical history of asbestos exposure, presented with a 27.2 cm upper abdominal mass and a 5.5 cm liver lesion. Retrospective review of the patient's abdominal CT scan 4 years ago showed two small abdominal lesions that were felt clinically to represent hemangiomas.
Source: Human Pathology - Category: Pathology Authors: Tags: Case study Source Type: research
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