HIV: ageing, cognition and neuroimaging at 4 ‐year follow‐up

ConclusionsIn the present study, we found some evidence for accelerated ageing in HIV‐positive individuals, with a statistically significant HIV status by age group interaction in global cognition, although this interaction could not be explained by the imaging findings. Moreover, we also found that change in cognitive performance was correlated with change in the DTI measures, and this effect was stronger for the HIV‐positive participants. This will need replication in larger studies using a similarly lengthy follow‐up period.

Source: HIV Medicine - February 1, 2018 Category: Infectious Diseases Authors: BI Haynes, M Pitkanen, R Kulasegaram, SJ Casey, M Schutte, K Towgood, B Peters, GJ Barker, MD Kopelman Tags: Original Research Source Type: research