Central amygdala neurons modulate pruritic processing

Itch is defined as an unpleasant sensation that evokes a desire to scratch. Recently, a surprising diversity of the sensory and spinal cord dorsal horn neurons that specifically process pruritic stimuli has been discovered. Despite this knowledge, our understandings of supraspinal mechanisms that are engaged in the itch processing are largely unknown. Here we took an unbiased approach using immediate early gene (cFos) mapping for precise dissection of brain circuits that mediate itch processing.
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research