Reversible atrioventricular block and the importance of close follow-up: Two cases of Lyme carditis

Publication date: Available online 13 February 2018 Source:Journal of Cardiology Cases Author(s): Anthony H. Kashou, Nabil Braiteh, Hisham E. Kashou Lyme carditis is an uncommon presentation of the early-disseminated phase of Lyme disease, although it is recognizable and often curable. Because of its rarity, diagnosing Lyme carditis requires a high level of suspicion, especially when young patients in certain endemic areas present with symptoms of bradycardia and/or evidence of high-degree atrioventricular (AV) block. Temporary cardiac pacing along with antibiotic therapy has been shown to aid in the management of Lyme carditis until symptoms and conduction blocks have resolved. Herein, we report two cases of Lyme carditis-induced AV block that were successfully managed and reversed with temporary cardiac pacing and antibiotics. In order to monitor for any late sequela that may arise, we also recommend close follow-up for patients treated for Lyme carditis with high-degree AV block. <Learning objective: Lyme carditis manifests as a conduction system disease, predominantly involving the atrioventricular (AV) node. It can present without the classical signs of Lyme disease. It is critical to have a high suspicion of Lyme carditis in patients who present with symptoms of bradycardia or high-degree AV block in high prevalence areas. Early initiation of antibiotics, along with external temporary pacing, dramatically improves mortality rates. Close follow-up is important in pat...
Source: Journal of Cardiology Cases - Category: Cardiology Source Type: research

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This study presented examples of base-calling DNA sequencing electropherograms routinely generated in a clinical diagnostic laboratory on DNA extracts of human blood specimens and ticks collected from human skin bites and from the environment. Since some of the tick samples tested were collected in Ireland, borrelial species or strains not known to exist in the United States were also detected by analysis of this 16S rRNA &ldquo;core genome&rdquo;. We recommend that hospital laboratories located in Lyme disease endemic areas begin to use a &ldquo;core genome&rdquo; sequencing test to routinely diagnose spir...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Authors: Figoni J, Chirouze C, Hansmann Y, Lemogne C, Hentgen V, Saunier A, Bouiller K, Gehanno JF, Rabaud C, Perrot S, Caumes E, Eldin C, de Broucker T, Jaulhac B, Roblot F, Toubiana J, Sellal F, Vuillemet F, Sordet C, Fantin B, Lina G, Gocko X, Dieudonné M, Bodaghi B, Gangneux JP, Degeilh B, Partouche H, Lenormand C, Sotto A, Raffetin A, Monsuez JJ, Michel C, Boulanger N, Cathebras P, Tattevin P, endorsed by scientific societies Abstract Lyme borreliosis is transmitted en France by the tick Ixodes ricinus, endemic in metropolitan France. In the absence of vaccine licensed for use in humans, primary prevent...
Source: Medecine et Maladies Infectieuses - Category: Infectious Diseases Tags: Med Mal Infect Source Type: research
Knowing the frequency of positive Lyme disease serology in children without signs of infection facilitates test interpretation. Of 315 asymptomatic children from Lyme disease endemic regions, 32 had positive or equivocal C6 enzyme-linked immunoassays, but only 5 had positive IgG or IgM supplemental immunoblots (1.6%; 95% confidence interval: 0.7%–3.7%).
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Brief Reports Source Type: research
a Szturcová Daniel Růžek Kurt Pfister Libor Grubhoffer In Europe, Lyme borreliosis (LB) and tick-borne encephalitis (TBE) are the two vector-borne diseases with the largest impact on human health. Based on data on the density of host-seeking Ixodes ricinus ticks and pathogen prevalence and using a variety of environmental data, we have created an acarological risk model for a region where both diseases are endemic (Czech Republic&mdash;South Bohemia and Germany&mdash;Lower Bavaria, Upper Palatinate). The data on tick density were acquired by flagging 50 sampling sites three times in a single seas...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
CONCLUSION: Older children and those with prolonged arthritis, arthritis limited to the knees, or poor initial response to antibiotics are more likely to have antibiotic-refractory disease and treatment-associated toxicity. Children with severe symptoms of systemic inflammation have more favorable outcomes. For children with persistently active Lyme arthritis after 2 antibiotic courses, pediatricians should consider starting antiinflammatory treatment and referring to a pediatric rheumatologist. PMID: 30824653 [PubMed - as supplied by publisher]
Source: Journal of Rheumatology - Category: Rheumatology Tags: J Rheumatol Source Type: research
Abstract The castor bean tick Ixodes ricinus is one of the most abundant tick species in Europe, being able to parasitize a wide number of vertebrate hosts, including mammals, birds, and reptiles. This tick species has an important role as vector of zoonotic pathogens, including the causative agents of Lyme borreliosis (i.e. Borrelia burgdorferi sensu lato). Here, we provide insights on a new tick-host association (i.e. I. ricinus infesting snakes) in an area recently recognized as endemic for reptile-associated zoonotic species of Borrelia burgdorferi s.l.. PMID: 30794772 [PubMed - as supplied by publisher]
Source: Acta Tropica - Category: Infectious Diseases Authors: Tags: Acta Trop Source Type: research
Source: Neurological Sciences - Category: Neurology Source Type: research
Purpose: The South Bohemian Region of the Czech Republic is an endemic area of tick-borne encephalitis (TBE). In 2017, the inhabitants of Římov municipality developed a serious course of TBE and Lyme borreliosis (LB). This led experts to research and serology examinations of the inhabitants of Římov in order to detect the seroprevalence of TBE and LB.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: 21.130 Source Type: research
We report 2 cases of severe babesiosis initially mistaken as malaria. The first patient was complicated by shock and splenic infarction, the other co-infected with Lyme disease. As the population traveling abroad increases every year, physicians should be aware of babesiosis which mimics malaria, co-infection with other diseases, and its complications. PMID: 30630283 [PubMed - in process]
Source: Korean Journal of Parasitology - Category: Parasitology Tags: Korean J Parasitol Source Type: research
Purpose of review To review the clinical diagnosis, management and natural history of septic arthritis of the hip (SAH) in the pediatric patient, and to highlight new information that may improve the management of these patients. Recent findings The basics of management of possible pediatric SAH have remained largely unchanged for generations. New questions have been raised regarding the role and timing of advanced imaging (MRI) in the evaluation of patients with possible SAH. Published criteria have been derived to guide the need for MRI studies in these patients. Validation of these guidelines continues. Recent revi...
Source: Current Opinion in Pediatrics - Category: Pediatrics Tags: ORTHOPEDICS: Edited by Daniel W. Green Source Type: research
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