L-arginine and Arginase Products Potentiate Dexmedetomidine-induced Contractions in the Rat Aorta

Conclusions These results suggest that when vascular nitric oxide homeostasis is impaired, the potentiation of the vasoconstrictor effect of dexmedetomidine byl-arginine depends on arginase activity and the production of urea and ornithine.
Source: Anesthesiology - Category: Anesthesiology Source Type: research