NIH study will assess biomarker as potential indicator of whether lower respiratory tract infections improve with antibacterial treatment

LRTIs can cause a variety of symptoms, including persistent coughing, wheezing, chest pain, fever, and rapid or difficult breathing.
Source: National Institutes of Health (NIH) News Releases - Category: American Health Source Type: news

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In this report, we looked at opioid medication use following discharge after radical prostatectomy. We found that 77% of opioid pain medication prescribed was unused, with 84% of patients using less than half of their prescription. Prescribing more opioids was associated with greater use; only 9% of patients appropriately disposed of leftover medication.
Source: European Urology - Category: Urology & Nephrology Source Type: research
Publication date: Available online 21 October 2018Source: Orthopaedics &Traumatology: Surgery &ResearchAuthor(s): Ali Zarezadeh, Kelly Mamelson, W. Christian Thomas, Bradley S. Schoch, Thomas W. Wright, Joseph J. KingAbstractIntroductionWe evaluate the most common outcome measures used in distal humerus fracture studies in order to suggest standardization for future research.Materials and methodsA systematic review identified articles assessing the outcomes of acute distal humerus fractures from 2006 to 2016 from PubMed and Web of Science databases. The inclusion criterion was studies reporting on the outcomes of t...
Source: Orthopaedics and Traumatology: Surgery and Research - Category: Orthopaedics Source Type: research
The Impact of Livestrong® at the YMCA for Cancer Survivors. Oncol Nurs Forum. 2018 Nov 01;45(6):717-725 Authors: Schumacher MM, McNiel P Abstract OBJECTIVES: To determine the clinical significance of pre- and post-exercise rehabilitation physical and psychosocial outcomes of the Livestrong® at the YMCA program. SAMPLE & SETTING: 158 participants at the YMCA of the Fox Cities in Appleton, Wisconsin, were analyzed for pre- and postparticipation physical outcomes, 68 participants were analyzed for pre- and postparticipation psychosocial outcomes, and 11 participants were interviewed abou...
Source: Oncology Nursing Forum - Category: Nursing Authors: Tags: Oncol Nurs Forum Source Type: research
CONCLUSION: Day-surgery is nowadays a concrete reality, made possible by an attentive selection of patients, an accurate surgical technique, an attentive patient monitoring in the postoperative period and a continuous monitoring of the effectiveness of pain medications. Over the last decades our surgical team has developed modified techniques of loco-regional anesthesia that allow us to perform even complex procedures and discharge the patient within 24 hours. KEY WORDS: Day-surgery, Haemorrhoids, Proctological procedures. PMID: 30337511 [PubMed - in process]
Source: Annali Italiani di Chirurgia - Category: Surgery Tags: Ann Ital Chir Source Type: research
CONCLUSIONS: Our results suggest that acetaminophen reduces the risk and intensity of persistent incisional pain. However, there are other mechanisms by which acetaminophen might reduce persistent pain. KEY WORDS: Anesthesia, acetaminophen, Persistent surgical pain, Postoperative acute pain. PMID: 30337510 [PubMed - in process]
Source: Annali Italiani di Chirurgia - Category: Surgery Tags: Ann Ital Chir Source Type: research
ConclusionsOur NLP system performed well in identifying the 26 lumbar spine findings, as benchmarked by reference-standard annotation by medical experts. Machine-learned models provided substantial gains in model sensitivity with slight loss of specificity, and overall higher AUC.
Source: Academic Radiology - Category: Radiology Source Type: research
In this study, eutectic mixtures, as binary pharmaceutical compositions of CEL with adipic acid (ADI) and saccharin (SAC), were identified through a phase diagram and Tammann’s triangle intended to improve the wettability and dissolution rate of poorly water-soluble CEL. The contact angles at 0s in the liquid-solid interface were approximately θs (theta) 79.7° ± 0.50° and 86.65° ± 0.45° for CEL-ADI and CEL-SAC, respectively, which were much lower than the value obtained for CEL (92.05° ± 0.75° θ). Moreover, a comparison of the disk intrinsic dissolution rate an...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
ConclusionMost potent three chemicals (ZA-2, 6 and 7) could be considered as bioactive to ensure the robust quality of the enriched fraction of ZAF with defined XO inhibition potential. Therefore, either single purified component or their enriched fraction could be a better choice for the management of gout than the crude extract of ZAF. Developed HPLC method is suitable for quality assurance analysis and process control of ZAF derived product intended for gout management. XO inhibitory potential exhibited by the characterized compounds validate the traditional use of this ZAF for the treatment of gout. Further, a detailed...
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 19 October 2018Source: Anaesthesia Critical Care &Pain MedicineAuthor(s): Eric Kipnis, Marc Leone
Source: Anaesthesia, Critical Care and Pain Medicine - Category: Anesthesiology Source Type: research
Publication date: Available online 19 October 2018Source: Anaesthesia Critical Care &Pain MedicineAuthor(s): Miet Schetz, Matthieu Legrand
Source: Anaesthesia, Critical Care and Pain Medicine - Category: Anesthesiology Source Type: research
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