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Mixed Results with PD Drug in Alzheimer's Psychosis (CME/CE)

(MedPage Today) -- Six-week improvement with pimavanserin didn't endure at 12 weeks
Source: MedPage Today Psychiatry - Category: Psychiatry Source Type: news

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Epidemiological studies suggest that a single moderate-to-severe traumatic brain injury (TBI) is associated with an increased risk of neurodegenerative disease, including Alzheimer's and Parkinson's disease (AD and PD). Histopathological studies describe c...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Dr. Huda Zoghbi, a Baylor College of Medicine professor whose work holds promise for treating a range of neurological and neuropsychiatric disorders, received an annual award for excellence in biological and biomedical sciences research from theDavid Geffen School of Medicine at UCLA.The medical school ’s dean, Dr. Kelsey Martin, presented Zoghbi with the 2017Switzer Prize during a Feb. 16 ceremony. Zoghbi received a $25,000 honorarium and a statuette.“Her story is a beautiful illustration of the connection between medicine and science, and a lesson in the value of maintaining curiosity and open-mindedness,&rdq...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Publication date: Available online 16 February 2018 Source:The Lancet Neurology Author(s): Shu-Ying Liu, Daryl J Wile, Jessie Fanglu Fu, Jason Valerio, Elham Shahinfard, Siobhan McCormick, Rostom Mabrouk, Nasim Vafai, Jess McKenzie, Nicole Neilson, Alexandra Perez-Soriano, Julieta E Arena, Mariya Cherkasova, Piu Chan, Jing Zhang, Cyrus P Zabetian, Jan O Aasly, Zbigniew K Wszolek, Martin J McKeown, Michael J Adam, Thomas J Ruth, Michael Schulzer, Vesna Sossi, A Jon Stoessl Background Markers of neuroinflammation are increased in some patients with LRRK2 Parkinson's disease compared with individuals with idiopathic Parkinso...
Source: The Lancet Neurology - Category: Neurology Source Type: research
New rules for the protection of nursing home residents have been implemented as part of the Affordable Care Act (ACA). Many of these rules provide answers to concerns that have troubled families with loved ones living in skilled nursing facilities (SNFs), generally called nursing homes. I emailed Medicare expert Ginalisa Monterroso for an update on these rules and what they mean for nursing home residents and their families. Read full article on HealthCentral about new rules to protect elders in nursinghomes that may disappear:  Support a caregiver or jump-start discussion in support groups with real stories - fo...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
Publication date: Available online 16 February 2018 Source:Pharmacological Research Author(s): Harald Hampel, Andrea Vergallo, Lisi Flores Aguilar, Norbert Benda, Karl Broich, A. Claudio Cuello, Jeffrey Cummings, Bruno Dubois, Howard J. Federoff, Massimo Fiandaca, Remy Genthon, Marion Haberkamp, Eric Karran, Mark Mapstone, George Perry, Lon S. Schneider, Lindsay A. Welikovitch, Janet Woodcock, Filippo Baldacci, Simone Lista The complex multifactorial nature of polygenic Alzheimer’s disease (AD) presents significant challenges for drug development. AD pathophysiology is progressing in a non-linear dynamic fashion acr...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
A drug commonly used to prevent mental decline in patients with dementia reportedly reversed the effects of alcohol exposure in adolescent rats, according to a Duke University study.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
People living with Alzheimer's or dementia can be moody, distrustful, stubborn, aggressive, and mean. Lets just say they become easily Discombobulated.by Bob DeMarcoAlzheimer's Reading RoomIt is very difficult to understand people living with Alzheimer's and dementia. It is very hard to adjust to the way they think, feel and act.One reason it is so difficlt is because they change.Meanwhile we don't change at all - do we?Change is hard to accept on any level, and the dramatic change that comes with Alzheimer's disease is even harder to accept.How to Change Patterns of Behavior in Alzheimer's and Dementia PatientsSubscribe t...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: alzheimer's world alzheimers Alzheimers Dementia care of alzheimers patients care of dementia patients discombobulated distrustful mean Source Type: blogs
Authors: Yang W, Chen X, Cohen DS, Rosin ER, Toga AW, Thompson PM, Huang X Abstract Alzheimer's disease (AD) is a progressive, and often fatal, brain disease that causes neurodegeneration, resulting in memory loss as well as other cognitive and behavioral problems. Here, we propose a novel multimodal method combining independent components from MRI measures and clinical assessments to distinguish Alzheimer's patients or mild cognitive impairment (MCI) subjects from healthy elderly controls. 70 AD subjects (mean age: 77.15 ± 6.2 years), 98 MCI subjects (mean age: 76.91 ± 5.7 years), and 150 HC subjects...
Source: International Journal of Clinical and Experimental Medicine - Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research
Older adults with poor fitness levels have more deterioration of white matter in their brains, according to a new study, compared with their fitter peers. White matter deterioration was also linked with a decline in decision-making brain function among adults with early signs of memory loss, suggesting that regular exercise may slow cognitive decline and perhaps even dementia, say the study authors. The study, published in the Journal of Alzheimer’s Disease, is not the first to suggest that exercise may help keep the brain healthy in old age. But while previous research has asked adults to self-report their fitness l...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Exercise/Fitness healthytime onetime Source Type: news
The first time scientists have been able to completely clear the brain of Alzheimer's-related protein tangles. → Explore PsyBlog's ebooks, all written by Dr Jeremy Dean: NEW: Accept Yourself: Self-Acceptance Practices For Emotional Healing Activate: How To Find Joy Again By Changing What You Do The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic Spark: 17 Steps That Will Boost Your Motivation For Anything
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Dementia Source Type: blogs
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