Mixed Results with PD Drug in Alzheimer's Psychosis (CME/CE)

(MedPage Today) -- Six-week improvement with pimavanserin didn't endure at 12 weeks
Source: MedPage Today Psychiatry - Category: Psychiatry Source Type: news

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A generic direct-to-consumer test box With Black Friday advertised low prices, are you purchasing Ancestry.com or 23andMe for all your relatives? If so, you soon may be one of the estimated 100 million consumers who will have direct-to-consumer (DTC) genetic testing by 2021.1 With improved technology and increased profits, consumer-directed companies promote easy and affordable tests for both ancestry and health information. However, both the general public and the health care provider community need to be aware of the potential utility and limitations of such tests. According to the Centers for Disease Cont...
Source: The Cornflower - Category: Databases & Libraries Authors: Tags: Blog Consumer Health From the GMR Source Type: news
Publication date: November–December 2018Source: Revista Española de Medicina Nuclear e Imagen Molecular (English Edition), Volume 37, Issue 6Author(s): David Garcia Solis
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - Category: Nuclear Medicine Source Type: research
A DNA vaccine slowed down the buildup of two types of toxin proteins associated with Alzheimer's disease, a study finds.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news
G protein-coupled receptor kinase 2 (GRK2), as a vital Ser/Thr kinase, is an important regulatory protein in the inflammatory immune response (IIR) by maintaining the balance between the function of inflammatory immune cells and non-conventional inflammatory immune cells and regulating inflammatory immune cell infiltration, inflammatory cytokine secretion, and the signaling associated with endothelial function. However, the imbalance of GRK2 expression and activity plays an important role in the development of IIR-related diseases, such as hypertension, heart failure, Alzheimer ’s disease, type 2 diabetes mellitus, i...
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research
Publication date: Available online 20 November 2018Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Zuo-Teng Wang, Chen-Chen Tan, Lan Tan, Jin-Tai YuAbstractGene mining has been a fruitful approach in the study of Alzheimer’s disease (AD). As a new starting point for studying AD, genetic and genomic investigations consistently strive to discover causative variants that are related to disease pathophysiology. Currently, genetic and genomic approaches have identified numerous loci. However, the elaboration of AD mechanism lagged behind gene discovery. The extensive use of parallel, high-throughput, next-genera...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
CONCLUSION: The clinical and neuropathological information to be obtained from this cohort in the future will provide a deeper understanding of the neuropathological mechanisms of cognitive impairment in Asia, especially Korea. PMID: 30450854 [PubMed - in process]
Source: Yonsei Medical Journal - Category: Universities & Medical Training Authors: Tags: Yonsei Med J Source Type: research
Condition:   Alzheimer Disease Intervention:   Drug: PTI-125 Sponsors:   Pain Therapeutics;   National Institutes of Health (NIH) Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Building on more than a decade of scientific research, a recent paper brings us one step closer to developing a vaccine for Alzheimer's disease.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Alzheimer's / Dementia Source Type: news
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Francesca Palombo, Francesco Masia, Sara Mattana, Francesco Tamagnini, Paola Borri, Wolfgang Langbein, Daniele Fioretto Non-negative factorization analysis applied to spontaneous Brillouin microscopy maps of amyloid-beta plaques in a transgenic mouse model enables to resolve spatially distinct components with specific mechanical properties. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - Category: Chemistry Authors: Source Type: research
Publication date: Available online 20 November 2018Source: NeuroImage: ClinicalAuthor(s): Colleen Rollins, Daniel Gallino, Vincent Kong, Gülebru Ayranci, Gabriel A. Devenyi, Jürgen Germann, M. Mallar ChakravartyAbstractObesity is recognized as a significant risk factor for Alzheimer's disease (AD). Studies have supported that obesity accelerates AD-related pathophysiology and memory impairment in mouse models of AD. However, the nature of the brain structure-behaviour relationship mediating this acceleration remains unclear. In this manuscript we evaluated the impact of adolescent obesity on the brain morphology ...
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
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