Downregulation of SPINK13 Promotes Metastasis by Regulating uPA in Ovarian Cancer Cells

Conclusion: These results indicate that SPINK13 functions as a tumour suppressor. The role of SPINK13 in cellular proliferation, apoptosis and migration is uPA dependent, and SPINK13 may be used as a potential biomarker for diagnosis and targeted therapy in OC.Cell Physiol Biochem 2018;45:1061 –1071
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research