Lipofilling as a Treatment for Vestibulodynia

Condition:   Vestibulodynia Interventions:   Procedure: Adipose derived stem cell transplantation via lipofilling;   Procedure: Surgical excision Sponsor:   University Hospital, Ghent Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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ConclusionHSCT could be an alternative and curative therapeutic option for selectedSTAT1 GOF mutant patients with progressive life-threatening disease unresponsive to conventional therapy. Morbidity and mortality-causing complications included secondary graft failure, infections, and bleeding.
Source: Journal of Clinical Immunology - Category: Allergy & Immunology Source Type: research
This article will explore PTLD and discuss the experience of caring for patients who developed lymphoproliferative conditions and required emergency stoma formation. The emotional and physical impact of surgery upon these patients, who have already experienced a protracted treatment journey, will be explored. Implications for practice for the lymphoma team and stoma nurse specialists involved with the care of these patients will also be considered. PMID: 30525969 [PubMed - in process]
Source: British Journal of Nursing - Category: Nursing Authors: Tags: Br J Nurs Source Type: research
Today's research results, published a few months ago, are one of a number of examples from recent years of a possible way to suppress or destroy persistent herpesviruses such as cytomegalovirus (CMV). These viruses cannot be effectively cleared from the body by the immune system; they remain latent to reemerge time and again. CMV itself is of particular interest because it is strongly implicated in the age-related dysfunction of the immune system. Research suggests that in old age an unsustainable fraction of immune cells become devoted to CMV, and since the decline of the thymus and hematopoietic stem cells ensure that th...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
SUMMARY Wernick's Encephalopathy (WE) is an acute neuropsychiatric syndrome caused by thiamine deficiency post hematopoietic stem cell transplant (HSCT). WE is associated with high mortality and morbidity rates, but due to its rare occurrence, it is rarely considered in patients submitted to this procedure. Considering that, the manuscript reports the clinical characteristics and the possible factors that predisposed the occurrence of WE in a patient with non-Hodgkin's lymphoma post-Autologous HSCT. We conclude that WE should be considered in patients submitted to autologous HSCT associated with prolonged use of TPN and malnutrition.
Source: Revista da Associacao Medica Brasileira - Category: General Medicine Source Type: research
SUMMARY Wernick's Encephalopathy (WE) is an acute neuropsychiatric syndrome caused by thiamine deficiency post hematopoietic stem cell transplant (HSCT). WE is associated with high mortality and morbidity rates, but due to its rare occurrence, it is rarely considered in patients submitted to this procedure. Considering that, the manuscript reports the clinical characteristics and the possible factors that predisposed the occurrence of WE in a patient with non-Hodgkin's lymphoma post-Autologous HSCT. We conclude that WE should be considered in patients submitted to autologous HSCT associated with prolonged use of TPN and malnutrition.
Source: Revista da Associacao Medica Brasileira - Category: General Medicine Source Type: research
Condition:   Graft vs Host Disease Intervention:   Drug: INC424 Sponsor:   Novartis Pharmaceuticals Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Retinal Degeneration;   Retinitis Pigmentosa;   Age Related Macular Degeneration;   Stargardt Disease 1 Intervention:   Biological: Stem/progenitor cells transplantation Sponsor:   Pomeranian Medical University Szczecin Enrolling by invitation
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Graft vs Host Disease Intervention:   Drug: INC424 Sponsor:   Novartis Pharmaceuticals Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
AbstractReconstitution of hepatocytes by hematopoietic stem cells —a phenomenon which occurs in rodents under highly selective conditions—results from infrequent fusion between incoming myelomonocytes and host hepatocytes, with subsequent proliferation. Human hematopoietic stem cell transplant recipients have been little studied, with some support for transdif ferentiation (direct differentiation). We studied routinely obtained autopsy liver tissue of four female hematopoietic cell transplant recipients with male donors, using a highly specific conjoint immunohistochemistry in situ hybridization light microscop...
Source: Virchows Archiv - Category: Pathology Source Type: research
AbstractAcute graft-versus-host disease (aGvHD) remains a major complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT). Prophylaxis with cyclosporine A (CsA) is the backbone of GvHD prevention. In a retrospective analysis of patients treated with allo-HSCT, we correlated CsA levels on the day of transplantation (day 0) and on day +  10 with the incidence of acute and chronic GvHD. We assessed 660 patients with either AMLn = 248, lymphoma/myeloman = 127, MDS/MPNn = 124, ALLn = 79, CLLn = 36, CMLn = 23, or bone ...
Source: Annals of Hematology - Category: Hematology Source Type: research
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