Can treatments for arthritis be repurposed for dementia? – Alzheimer’s Society comments

New research suggests that drugs used to treat rheumatoid arthritis could reduce the risk of patients developing dementia.
Source: Alzheimers Society - Category: Geriatrics Source Type: news

Related Links:

See something of interest? Please share our postings with colleagues in your institutions! Spotlight The MAReport: Check out the Spring 2018 issue of the MAReport newsletter! This quarter, Academic Coordinator Elaina Vitale talked about using evidence-based resources to improve citations on Wikipedia, and her experience with NNLM’s first virtual Wikipedia Edit-a-thon. National Network of Libraries of Medicine News Dementia and Alzheimer’s Services @ Your Library – Midwest Matters, from GMR The next round of PubMed for Librarians begins August 29. Register for any (or all) of the PML classes to learn ...
Source: NN/LM Middle Atlantic Region Blog - Category: Databases & Libraries Authors: Tags: Weekly Postings Source Type: news
Publication date: Available online 10 July 2018Source: Autoimmunity ReviewsAuthor(s): Alice Mason, Clive Holmes, Christopher J. EdwardsAbstractDementia is a major international public health problem which looks set to grow as the ageing population increases. Despite large amounts of investment there has been relatively little progress in developing new therapies to combat this. There is a growing body of evidence that both local and systemic inflammation are important in dementia; with cerebral inflammation occurring secondarily to beta-amyloid plaques, raised levels of serum inflammatory molecules and cytokines being pres...
Source: Autoimmunity Reviews - Category: Allergy & Immunology Source Type: research
Abstract Longer lifespan is accompanied by a larger number of chronic diseases among older adults. Because of a growing proportion of older adults in the U.S., this brings the problem of age-related morbidity to the forefront as a major contributor to rising medical expenditures. We evaluated 15-year time trends (from 1998 to 2013) in the prevalence of 48 acute and chronic non-cancer diseases and cancers in older U.S. adults aged 65+ and estimated the annual percentage changes of these prevalence trends using SEER-Medicare and HRS-Medicare data. We found that age-adjusted prevalence of cancers of kidney, pancreas,...
Source: Experimental Gerontology - Category: Geriatrics Authors: Tags: Exp Gerontol Source Type: research
This study indicates that frailty and other age-related diseases could be prevented and significantly reduced in older adults. Getting our heart risk factors under control could lead to much healthier old ages. Unfortunately, the current obesity epidemic is moving the older population in the wrong direction, however our study underlines how even small reductions in risk are worthwhile." The study analysed data from more than 421,000 people aged 60-69 in both GP medical records and in the UK Biobank research study. Participants were followed up over ten years. The researchers analysed six factors that could impa...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In conclusion, in the Framingham Heart Study population, in the last 30 years, disease duration in persons with dementia has decreased. However, age-adjusted mortality risk has slightly decreased after 1977-1983. Consequences of such trends on dementia prevalence should be investigated. Recent Research on the Benefits of Exercise in Later Life https://www.fightaging.org/archives/2018/04/recent-research-on-the-benefits-of-exercise-in-later-life/ A sizable body of work points to the ability of older individuals to continue to obtain benefits through regular physical activity, and particularly in the case ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In conclusion, the present study demonstrated that TIGIT is a prominent negative immune regulator involved in immunosenescence. This novel finding is highly significant, as targeting TIGIT might be an effective strategy to improve the immune response and decrease age-related comorbidities. Delivery of Extracellular Vesicles as a Potential Basis for Therapies https://www.fightaging.org/archives/2018/01/delivery-of-extracellular-vesicles-as-a-potential-basis-for-therapies/ Here I'll point out a readable open access review paper on the potential use of extracellular vesicles as a basis for therapy: harveste...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In conclusion, documentation is important, a critical part of advocacy and the development process at the larger scale. It isn't just words, but rather a vital structural flow of information from one part of the larger community to another, necessary to sustain progress in any complex field. We would all do well to remember this - and to see that building this documentation is an activity in which we can all pitch in to help. Evidence Suggests that, at Least in Earlier Stages, Alzheimer's Disease Blocks Rather than Destroys Memories https://www.fightaging.org/archives/2017/07/evidence-suggests-that-at-least-in-ea...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Chronic lack of sleep makes it hard to focus on a task. As if this didn’t make complete logical sense, multiple research studies have shown that sleep deprivation has about the same effect on our cognition and coordination as a few alcoholic beverages. What do you do when you need to concentrate, but you’re tired? Many of us reach for a cup of coffee, or a soda. Mountains of solid research have shown us that caffeine (in doses ranging between 30 and 300 milligrams) improves attention, alertness, reaction time, and mood, especially when we’re tired. An average cup of brewed coffee contains between 80 and 1...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Behavioral Health Exercise and Fitness Source Type: blogs
Objective To determine whether hospital admission for autoimmune disease is associated with an elevated risk of future admission for dementia. Methods Retrospective, record-linkage cohort study using national hospital care and mortality administrative data, 1999–2012. Cohorts of people admitted to hospital with a range of autoimmune diseases were constructed, along with a control cohort, and followed forward in time to see if they developed dementia. 1 833 827 people were admitted to hospital with an autoimmune disease; the number of people in cohorts for each autoimmune disease ranged from 1019 people in ...
Source: Journal of Epidemiology and Community Health - Category: Epidemiology Authors: Tags: Press releases Research reports Source Type: research
More News: Alzheimer's | Arthritis | Dementia | Geriatrics | Rheumatoid Arthritis | Rheumatology