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Can treatments for arthritis be repurposed for dementia? – Alzheimer’s Society comments

New research suggests that drugs used to treat rheumatoid arthritis could reduce the risk of patients developing dementia.
Source: Alzheimers Society - Category: Geriatrics Source Type: news

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In conclusion, in the Framingham Heart Study population, in the last 30 years, disease duration in persons with dementia has decreased. However, age-adjusted mortality risk has slightly decreased after 1977-1983. Consequences of such trends on dementia prevalence should be investigated. Recent Research on the Benefits of Exercise in Later Life https://www.fightaging.org/archives/2018/04/recent-research-on-the-benefits-of-exercise-in-later-life/ A sizable body of work points to the ability of older individuals to continue to obtain benefits through regular physical activity, and particularly in the case ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In conclusion, the present study demonstrated that TIGIT is a prominent negative immune regulator involved in immunosenescence. This novel finding is highly significant, as targeting TIGIT might be an effective strategy to improve the immune response and decrease age-related comorbidities. Delivery of Extracellular Vesicles as a Potential Basis for Therapies https://www.fightaging.org/archives/2018/01/delivery-of-extracellular-vesicles-as-a-potential-basis-for-therapies/ Here I'll point out a readable open access review paper on the potential use of extracellular vesicles as a basis for therapy: harveste...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In conclusion, documentation is important, a critical part of advocacy and the development process at the larger scale. It isn't just words, but rather a vital structural flow of information from one part of the larger community to another, necessary to sustain progress in any complex field. We would all do well to remember this - and to see that building this documentation is an activity in which we can all pitch in to help. Evidence Suggests that, at Least in Earlier Stages, Alzheimer's Disease Blocks Rather than Destroys Memories https://www.fightaging.org/archives/2017/07/evidence-suggests-that-at-least-in-ea...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Chronic lack of sleep makes it hard to focus on a task. As if this didn’t make complete logical sense, multiple research studies have shown that sleep deprivation has about the same effect on our cognition and coordination as a few alcoholic beverages. What do you do when you need to concentrate, but you’re tired? Many of us reach for a cup of coffee, or a soda. Mountains of solid research have shown us that caffeine (in doses ranging between 30 and 300 milligrams) improves attention, alertness, reaction time, and mood, especially when we’re tired. An average cup of brewed coffee contains between 80 and 1...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Behavioral Health Exercise and Fitness Source Type: blogs
Objective To determine whether hospital admission for autoimmune disease is associated with an elevated risk of future admission for dementia. Methods Retrospective, record-linkage cohort study using national hospital care and mortality administrative data, 1999–2012. Cohorts of people admitted to hospital with a range of autoimmune diseases were constructed, along with a control cohort, and followed forward in time to see if they developed dementia. 1 833 827 people were admitted to hospital with an autoimmune disease; the number of people in cohorts for each autoimmune disease ranged from 1019 people in ...
Source: Journal of Epidemiology and Community Health - Category: Epidemiology Authors: Tags: Press releases Research reports Source Type: research
It’s MS Awareness Week in the United States — the time of year that the National Multiple Sclerosis Society and people living with MS try to spread awareness of this disease. For the past several years, I’ve determined to spend this week educating people who live with MS about the disease they have. For past MS awareness weeks, I’ve written pieces on MS history and about the first recorded cases of MS. Today I write about research suggesting what might be in some of our futures. It’s not a happy topic, but I believe that forewarned is forearmed. A recent study pub...
Source: Life with MS - Category: Neurology Authors: Tags: multiple sclerosis awareness life with MS Living with MS MS and family MS symptoms trevis gleason Source Type: blogs
A new study linking autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis, and later dementia strengthens the hypothesis that Alzheimer's may have an autoimmune component, researchers say.Medscape Medical News
Source: Medscape Neurology and Neurosurgery Headlines - Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news
Dear Carol: Last year Christmas was a mess and I’m determined to make this year better. Dad had a stroke two years ago and uses a wheelchair and mom has rheumatoid arthritis and uses a walker, so they both need a place with easy access. That would be my house. Both of my brothers, their wives, and their children join us. Along with our kids, the total of children is five. They are good kids but noisy which bothers my dad. Also, my brothers have opposing political views so I’m praying they don’t get into politics. To make things even more complicated, Mom is super judgmental and finds something to com...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
Conclusion: Despite the significant burden mental disorders impose on society, investment and pharmaceutical innovation in this disease area remains comparatively low. Policymakers should consider new strategies to stimulate public and private investment in the research and development of novel and effective therapies to treat schizophrenia and other mental disorders. Introduction Over the last two decades, there have been remarkable breakthroughs in healthcare. These breakthroughs include the development of novel pharmaceutical treatments that have significantly improved outcomes for patients suffering from various medica...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Bipolar Disorder Current Issue Drug Development Mental Disorders Mood Disorders Original Research Psychiatry Psychopharmacology disease burden expenditures major depressive disorder pharmaceutical innovation research and developmen Source Type: research
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