Improving immunotherapy outcomes with anti-angiogenic treatments and vice versa

Improving immunotherapy outcomes with anti-angiogenic treatments and vice versaImproving immunotherapy outcomes with anti-angiogenic treatments and vice versa, Published online: 13 February 2018; doi:10.1038/nrclinonc.2018.9The combination of immunotherapies with other therapeutic modalities, including anti-angiogenic agents, is currently under investigation to improve the outcomes of patients receiving immunotherapies. In this article, the authors review the effects mediated by anti-angiogenic agents that might increase the efficacy of immunotherapies and discuss the possibility that immunotherapies might increase the efficacy of anti-angiogenic agents and/or promote changes in the tumour vasculature.
Source: Nature Clinical Practice Oncology - Category: Cancer & Oncology Authors: Source Type: research