A membrane-type surfactant protein D (SP-D) suppresses macrophage-mediated cytotoxicity in swine endothelial cells.

CONCLUSIONS: These findings indicate that the membrane-type SP-D serve as an effective therapeutic strategy for inhibiting macrophage-mediated xenograft rejection in xenotransplantation.
PMID: 29425774 [PubMed - as supplied by publisher]

Source: Transplant Immunology - February 6, 2018 Category: Transplant Surgery Authors: Jiaravuthisan P, Maeda A, Takakura C, Wang HT, Sakai R, Shabri AM, Lo PC, Matsuura R, Kodama T, Eguchi H, Okuyama H, Miyagawa S Tags: Transpl Immunol Source Type: research