Identifying Potential Quality Markers of Xin-Su-Ning Capsules Acting on Arrhythmia by Integrating UHPLC-LTQ-Orbitrap, ADME Prediction and Network Target Analysis

Conclusion Our integrative pharmacology-based approach combining UHPLC-LTQ-Orbitrap, in silico ADME prediction and network target analysis may be efficient to identify potential Q-markers of TCM prescriptions. Our data showed that berberine, palmatine, scopoletin, liquiritigenin, naringenin, formononetin, nobiletin, tangeretin, 5-demethylnobiletin, kushenol E and kurarinone might function as candidate markers for qualitative evaluation of XSNC. Graphical abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research