Nasal IL-25 predicts the response to oral corticosteroids in chronic rhinosinusitis with nasal polyps

Oral corticosteroids are commonly used in the treatment of chronic rhinosinusitis with nasal polyps (CRSwNP).1 However, the efficacy of oral-corticosteroid therapy varies between different patients with CRSwNP. IL-25 –mediated TH2-biased response is reported to be associated with corticosteroid sensitivity in airway inflammatory response,2 while their value for predicting oral-corticosteroid response to CRSwNP has not been completely evaluated.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Tags: Letter to the Editor Source Type: research