Nasal IL-25 predicts the response to oral corticosteroids in chronic rhinosinusitis with nasal polyps
Oral corticosteroids are commonly used in the treatment of chronic rhinosinusitis with nasal polyps (CRSwNP).1 However, the efficacy of oral-corticosteroid therapy varies between different patients with CRSwNP. IL-25 –mediated TH2-biased response is reported to be associated with corticosteroid sensitivity in airway inflammatory response,2 while their value for predicting oral-corticosteroid response to CRSwNP has not been completely evaluated.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Haiyu Hong, Fenghong Chen, Yueqi Sun, Qintai Yang, Wenxiang Gao, Yujie Cao, Yunping Fan, Jianbo Shi, Huabin Li Tags: Letter to the Editor Source Type: research