Comparison of two exhaled biomarkers in children with and without sleep disordered breathing

Airway oxidative stress and inflammation are likely to be involved in sleep disordered breathing (SDB) in children. We aimed to measure concentrations of 8-isoprostane (8-IsoP) in the exhaled breath condensate (EBC) and exhaled nitric oxide (FENO) in patients with SBD and healthy children, in order to assess the relationship between these two biomarkers, disease severity, and overnight changes.

Source: Sleep Medicine - February 10, 2018 Category: Sleep Medicine Authors: Mario Barreto, Paolo Montuschi, Melania Evangelisti, Susanna Bonafoni, Manuela Cecili, Rugia Shohreh, Giuseppe Santini, Maria Pia Villa Tags: Original Article Source Type: research