Berberine encapsulated PLGA-PEG nanoparticles modulates PCSK-9 in HepG2 cells.

CONCLUSION: Nanotechnology drug delivery approach of Berberine modulates PCSK-9 in HepG2 cells, this approach may result in improving the drug pharmacokinetic performance and the intended target outcome. Further studies in animal models are needed to validate this result and explore the potential mechanistic components and function. PMID: 29422010 [PubMed - as supplied by publisher]
Source: Cardiovascular and Hematological Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Cardiovasc Hematol Disord Drug Targets Source Type: research