The Visible Burrow System: a behavioral paradigm to assess sociability and social withdrawal in BTBR and C57BL/6J mice strains.

In conclusion, our study validated the use of the VBS as an ethologically relevant behavioral paradigm in group-housed mice to investigate individual sociability and social withdrawal features and their underlying neurobiology. This paradigm may provide new insights to develop new therapeutic treatments for behavioral dysfunctions that may be relevant across neuropsychiatric diseases.
PMID: 29425919 [PubMed - as supplied by publisher]

Source: Behavioural Brain Research - February 6, 2018 Category: Neurology Authors: Bove M, Ike K, Eldering A, Buwalda B, de Boer SF, Morgese MG, Schiavone S, Cuomo V, Trabace L, Kas MJH Tags: Behav Brain Res Source Type: research