Hormonal factors and pancreatic cancer risk in women: The Malm ö Diet and Cancer Study

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Source: International Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Research Article Source Type: research

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Travel writer Ileana von Hirsch discovered that the experience of having cancer can have its comedic moments - and finding them makes all the difference.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
It is critical for survival to assign positive or negative valence to salient stimuli in a correct manner. Accordingly, harmful stimuli and internal states characterized by perturbed homeostasis are accompanied by discomfort, unease, and aversion. Aversive signaling causes extensive suffering during chronic diseases, including inflammatory conditions, cancer, and depression. Here, we investigated the role of melanocortin 4 receptors (MC4Rs) in aversive processing using genetically modified mice and a behavioral test in which mice avoid an environment that they have learned to associate with aversive stimuli. In normal mice...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Receptor tyrosine kinases (RTKs) are important drivers of cancers. In addition to genomic alterations, aberrant activation of WT RTKs plays an important role in driving cancer progression. However, the mechanisms underlying how RTKs drive prostate cancer remain incompletely characterized. Here we show that non-proteolytic ubiquitination of RTK regulates its kinase activity and contributes to RTK-mediated prostate cancer metastasis. TRAF4, an E3 ubiquitin ligase, is highly expressed in metastatic prostate cancer. We demonstrated here that it is a key player in regulating RTK-mediated prostate cancer metastasis. We further i...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
New J. Chem., 2018, Advance Article DOI: 10.1039/C8NJ01713A, PaperTania Lozano-Cruz, Rafael Gomez, F. Javier de la Mata, Paula Ortega A water soluble "bow-tie" cationic carbosilane dendrimer with curcumin in the core displays antioxidant and antitumoral activities against breast cancer cells. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - Category: Chemistry Authors: Source Type: research
Abstract Transfeminine individuals are treated with estradiol and anti-androgen agents to transition to a more feminine appearance. The physical changes that occur with estradiol therapy include breast development, body fat redistribution, and decreased muscle mass. Transfeminine treatment regimens require monitoring and dose adjustments to achieve appropriate physiologic targets to enhance feminization and decrease risk of adverse outcomes. Adverse effects associated with estradiol use include thromboembolic disease, macroprolactinoma, breast cancer, coronary artery disease, cerebrovascular disease, cholelithiasi...
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Tags: Clin Plast Surg Source Type: research
Dewayne Joihnson, 46, of California, is the first person to go to trial claiming that weed killer Roundup is responsible for his cancer diagnosis while maker Monsanto denies these claims.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Author Affiliations open 1 McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Canada 2 Barcelona Institute for Global Health (ISGlobal), Barcelona, Spain 3 Universitat Pompeu Fabra (UPF), Barcelona, Spain 4 CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain 5 School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada 6 Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA 7 Department of Economics, Brigham Young University, Provo, Utah, USA 8 Population Studies Division, Health Canada, Ottawa, Cana...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
By now, most people have been to a holiday party or two. Lots of food, lots of eggnog and other carb laden alcoholic beverages, and lots of grazing all day long on all the boxes of candy friends and business acquaintances sent to us. It's easy to gain the five pounds most people gain during the holidays, and in the process, raise your blood sugar or glucose levels too high. That's your body letting you know you have prediabetes (higher than normal but still below diabetes levels) or diabetes, and unless you take action soon, your body won't like it. Diabetes silently sneaks up on you and if untreated, slowly weakens your ...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
This study found that overall, 20% to 40% of carcinoma cases and about half of carcinoma deaths could potentially be prevented through certain lifestyle modifications. Here are the 4 lifestyle behaviors that if practiced throughout a lifetime, were found to be linked to a lower rate of cancer incidence and death: 1. Don't smoke The study revealed that smoking contributed to 48.5% of deaths from the 12 smoking-related cancers in the United States including lung, pancreas, bladder, stomach, colon/rectal and esophagus. The message here is plain and simple -- don't ever start smoking and if you already are, quit. Smoking ...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
Obesity is a serious and costly public health problem. In 2009-2010, more than one-third of U.S. adults (35.7%) and 17% of youth were reported to be obese. The epidemiological data suggest that obesity is markedly different among multiple racial and ethnic populations. According to the United States Centers for Disease Control and Prevention (CDC) reports, Non-Hispanic blacks have the highest age-adjusted rates of obesity (47.8%) followed by Hispanics (42.5%), non-Hispanic whites (32.6%), and non-Hispanic Asians (10.8%). Higher prevalence of adult obesity was found in the Midwest (29.5%) and the South (29.4%). Lower preval...
Source: Cancer Epidemiology Biomarkers and Prevention - Category: Cancer & Oncology Authors: Tags: Obesity, Metabolism, and Cancer: Oral Presentations - Invited Abstracts Source Type: research
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