Hormonal factors and pancreatic cancer risk in women: The Malm ö Diet and Cancer Study

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Source: International Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Research Article Source Type: research

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Publication date: Available online 22 September 2018Source: Biosensors and BioelectronicsAuthor(s): Nan Zhou, Fangfang Su, Chuanpan Guo, Linghao He, Zhankui Jia, Minghua Wang, Qiaojuan Jia, Zhihong Zhang, Siyu LuAbstractFabricating novel bimetallic metal organic framework (MOF) architectures and exploiting them as aptasensor scaffolds for detecting diverse analytes, especially cancer markers, have aroused widespread research attention. Herein, we report a novel strategy for obtaining ZnZr bimetallic MOFs via the MOF-on-MOF method and exploit them as an aptasensor platform for detecting the cancer marker protein tyrosine ki...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
Publication date: Available online 21 September 2018Source: Biosensors and BioelectronicsAuthor(s): Yue Zheng, Xiaoyu Wang, Shengquan He, Zehua Gao, Ya Di, Kunling Lu, Kun Li, Jidong WangAbstractA electrochemical biosensing strategy was developed for green and ultrasensitive detection of tumor cells by combining aptamer-DNA concatamer-CdTe quantum dots (QDs) signal amplification probe with mercury-free anodic stripping voltammetry (ASV). First, aptamer-DNA concatamer- CdTe QDs probes were designed by DNA hybridization and covalent assembling, which contained specific recognition of aptamer and signal amplification incorpor...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
Publication date: Available online 21 September 2018Source: Biosensors and BioelectronicsAuthor(s): Wei Wei, Wei Zhang, Chuanyu Li, Hui Kong, Zhen Guo, Zhiqi Zhang, François Bastien, Yuehua Gong, Hongchao Wang, Lianqun ZhouAbstractEarly screening of gastric cancer is a critical importance for the improvement of patients’ survival rate. Here, a polyethylene coating Lamb (PE-Lamb) microfluidic device with immune layer for gastric cancer label-free detection was constructed. Two serum pepsinogen 1 (PG1) and pepsinogen 2 (PG2) biomarkers were applied to screen and predict the appearance of gastric cancer. Compared...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
Publication date: Available online 17 September 2018Source: Sensors and Actuators B: ChemicalAuthor(s): Seong-Eun Kim, Young Joo Kim, Sunga Song, Kook-Nyung Lee, Woo Kyeong SeongAbstractBladder cancer is one of the tumors associated with the highest mortality rate. It is clinically characterized by high recurrent rates and poor prognosis once tumors invade the lamina propia. Nevertheless, current diagnostic techniques such as cystoscopy and cytology are invasive, time-consuming, and expensive. To address these challenges, we developed an electrochemical enzyme-linked immunosorbent assay (eELISA) platform on indium tin oxid...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
Publication date: October 2018Source: Phytochemistry Letters, Volume 27Author(s): Moustafa T. Gabr, Mohammed S. Abdel-RaziqAbstractNew series of arylsparteine derivatives were synthesized and evaluated for their cytotoxic activity against four human cancer cell lines (cervical epithelial carcinoma cells Hela, breast cancer cells MCF-7, lung cancer cells A549, and glioma cells U87 MG) and one normal fibroblast cell line. Structure-activity relationship revealed that introduction of 4-quinolinyl moiety to sparteine afforded a hybrid compound 10 with considerable antiproliferative activity against all tested cancer cell lines...
Source: Phytochemistry Letters - Category: Chemistry Source Type: research
Publication date: October 2018Source: Phytochemistry Letters, Volume 27Author(s): Hoang Le Tuan Anh, Do Thi Thao, Duong Thi Dung, Phan Van Kiem, Tran Hong Quang, Pham Thi Hai Yen, Do Thanh Tuan, Pham Viet Cuong, Le Canh Viet Cuong, Tran Manh HungAbstractA comprehensive phytochemical investigation of the dichloromethane-soluble fraction of Physalis angulata led to the isolation of eight compounds (1–8) including two new withanolides named physagulin P and Q (compounds 5 and 8). Their chemical structures were established using two-dimensional nuclear magnetic resonance (spectroscopy. The cytotoxic activity of these met...
Source: Phytochemistry Letters - Category: Chemistry Source Type: research
Author Affiliations open 1 McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Canada 2 Barcelona Institute for Global Health (ISGlobal), Barcelona, Spain 3 Universitat Pompeu Fabra (UPF), Barcelona, Spain 4 CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain 5 School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada 6 Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA 7 Department of Economics, Brigham Young University, Provo, Utah, USA 8 Population Studies Division, Health Canada, Ottawa, Cana...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
By now, most people have been to a holiday party or two. Lots of food, lots of eggnog and other carb laden alcoholic beverages, and lots of grazing all day long on all the boxes of candy friends and business acquaintances sent to us. It's easy to gain the five pounds most people gain during the holidays, and in the process, raise your blood sugar or glucose levels too high. That's your body letting you know you have prediabetes (higher than normal but still below diabetes levels) or diabetes, and unless you take action soon, your body won't like it. Diabetes silently sneaks up on you and if untreated, slowly weakens your ...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
This study found that overall, 20% to 40% of carcinoma cases and about half of carcinoma deaths could potentially be prevented through certain lifestyle modifications. Here are the 4 lifestyle behaviors that if practiced throughout a lifetime, were found to be linked to a lower rate of cancer incidence and death: 1. Don't smoke The study revealed that smoking contributed to 48.5% of deaths from the 12 smoking-related cancers in the United States including lung, pancreas, bladder, stomach, colon/rectal and esophagus. The message here is plain and simple -- don't ever start smoking and if you already are, quit. Smoking ...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
Obesity is a serious and costly public health problem. In 2009-2010, more than one-third of U.S. adults (35.7%) and 17% of youth were reported to be obese. The epidemiological data suggest that obesity is markedly different among multiple racial and ethnic populations. According to the United States Centers for Disease Control and Prevention (CDC) reports, Non-Hispanic blacks have the highest age-adjusted rates of obesity (47.8%) followed by Hispanics (42.5%), non-Hispanic whites (32.6%), and non-Hispanic Asians (10.8%). Higher prevalence of adult obesity was found in the Midwest (29.5%) and the South (29.4%). Lower preval...
Source: Cancer Epidemiology Biomarkers and Prevention - Category: Cancer & Oncology Authors: Tags: Obesity, Metabolism, and Cancer: Oral Presentations - Invited Abstracts Source Type: research
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