Medical News Today: Vitamin B-3 could be used to treat Alzheimer's
New research finds that nicotinamide riboside, which is a form of vitamin B-3, has the potential to treat Alzheimer's. Results in mice are hopeful.
Introduction: Frontotemporal lobar degeneration (FTLD)-related syndrome includes progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS). PSP is usually caused by a tauopathy but can have associated Alzheimer's disease (AD) while CBS can be caused by tauopathy, transactive response DNA binding protein 43 kDa, or AD pathology. Our aim was to compare the parkinsonian syndromes presenting without AD biomarkers (CBS/PSP-non-AD) to parkinsonian syndromes with AD biomarkers (CBS/PSP-AD).Materials and Methods: Twenty-four patients [11 males, 13 females; age (68.46 ± 7.23)] were recruited for this study. The wh...
The objective of this study was to analyze the relationship between brain complexity and the presence of ApoE ε 4 alleles along the AD continuum. For this purpose, resting-state electroencephalography (EEG) activity was analyzed by computing Lempel-Ziv complexity (LZC) from 46 healthy control subjects, 49 mild cognitive impairment subjects, 45 mild AD patients, 44 moderate AD patients and 33 severe AD patients, subdivided by ApoE status. Subjects with one or more ApoE ε 4 alleles were included in the carriers subgroups, whereas the ApoE ε 4 non-carriers subgroups were formed by subjects ...
Condition: Agitation in Patients With Dementia of the Alzheimer's Type Interventions: Drug: AVP-786; Drug: Placebo Sponsor: Avanir Pharmaceuticals Not yet recruiting
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VASCULAR dementia affects around 150,000 people in the UK, according to Alzheimer's Society. Brain damage occurs as blood supply is restricted to the complex organ. Here is the early warning sign you've been affected.
Authors: Meyer A, Handabaka I, Ehrensperger MM, Gschwandtner U, Hatz F, Monsch AU, Stieglitz RD, Fuhr P Abstract OBJECTIVE: The first (primacy region) and last (recency region) items of a word list are generally better memorized than items from the middle region. The recency effect depends on short-term memory (STM) and the primacy effect on long-term memory (LTM), where verbal information is transferred from STM into LTM by maintenance rehearsal. We compared the serial position effects (SPE) between patients with mild cognitive impairment (MCI) due to Parkinson's disease (PD), i.e., PD-MCI, and patients with MCI d...
DEMENTIA symptoms include difficulty concentrating, mood changes, and having slower thoughts. But, you could also be at risk of Alzheimer's disease if you notice a subtle change to the way you walk. When should you consider speaking to a doctor about Alzheimer's disease symptoms?
Older adults with both hearing and visual impairment have a nearly 90 percent higher risk for developing dementia, according to a study in the journal Alzheimer's&Dementia: Diagnosis, Assessment&Disease Monitoring.
(Wiley) Older adults with both hearing and visual impairments--or dual sensory impairment--had a significantly higher risk for dementia in a recent study published in Alzheimer's&Dementia: Diagnosis, Assessment&Disease Monitoring.
Brain aging is a major risk factor in the progression of cognitive diseases including Alzheimer ’s disease (AD) and vascular dementia. We investigated a mouse model of brain aging up to 24 months old (mo).