Scientists Create First Lab-Grown Human Eggs

U.K. researchers who created the first laboratory-grown human eggs say their achievement could lead to news ways to preserve the fertility of girls undergoing radiation or chemotherapy for cancer.
Source: WebMD Health - Category: Consumer Health News Source Type: news

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April Doyle, a single mom from Visalia, Cal., only lets herself look three months into her future. Since she was first diagnosed with breast cancer in 2014, she’s tried a new treatment every three months to keep the cancer from spreading from her breast tissue to other parts of her body. But it returned: this time in her bone. She is almost out of options for her hard-to-treat cancer, but she finds comfort in online support groups where other women with metastatic breast cancer share their experiences. “Eventually we know we will exhaust all of our options until they keep coming up with more treatments,” ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Cancer healthytime Source Type: news
Noncolorectal gastrointestinal (GI) malignancies are among the most frequently diagnosed cancers. Despite the undeniable progress in systemic treatments in recent decades, further improvements using cytotoxic chemotherapy seem unlikely. In this setting, recent discoveries regarding the mechanism underlying immune evasion have prompted the study of molecules capable of inducing strong antitumor responses. Thus, according to early data, immunotherapy is a very promising tool for the treatment of patients with GI malignancies. Noncolorectal GI cancers are a major public health problem worldwide. Traditional treatment options,...
Source: Clinics - Category: General Medicine Source Type: research
We report the case of a 64-year-old White woman with a metastatic melanoma undergoing second-line treatment with pembrolizumab. At first evaluation, after 3 months of therapy, computed tomography scans showed the onset of osteosclerotic lesions and a significant reduction in all the previously identified metastases; on the contrary, a fluorine-18-fluorodeoxyglucose PET showed the normalization of fluorine-18-fluorodeoxyglucose uptake in all the baseline lesions, including bone metastases. Osteoblastic response, consisting of occurrence of new osteoblastic lesions on computed tomography imaging, as a consequence of an osteo...
Source: Anti-Cancer Drugs - Category: Cancer & Oncology Tags: CASE REPORT Source Type: research
This study aims to analyse trends in the use of neoadjuvant chemotherapy (NAC) and the impact on surgical outcomes.MethodsWe reviewed all records of cT1-4N1-3M0 breast cancer patients diagnosed between July 2011 and June 2016 who have been registered in the Dutch National Breast Cancer Audit (NBCA) (N = 57.177). The surgical outcomes of 'BCS after NAC′ were compared with 'primary BCS′, using a multivariable logistic regression model.ResultsBetween 2011 and 2016, the use of NAC increased from 9% to 18% and 'BCS after NAC' (N = 4170) increased from 43% to 57%. We observed an involved invasive margin rate ...
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
ConclusionSubstantial treatment differences are observed across North European countries for patients with stages II and III resectable gastric cancer aged 70 years or older. In the present comparison, treatment strategies with a higher proportion of patients undergoing surgery seemed to be associated with higher survival rates for patients with stages II or III disease.
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
ConclusionWe developed a predictive model using machine learning that could represent a useful and easy-to-access tool for the selection of high ODX RS patients. After additional evaluation with large data and external validation, worldwide use of our model could be expected.
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
ConclusionCRS/HIPEC is a safe and effective approach in selected patients with PM of HCC. CRS/HIPEC gives the patient a chance for a good relapse free and overall survival and should be considered as an option.
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
Publication date: November 2018Source: European Journal of Surgical Oncology, Volume 44, Issue 11Author(s): Baek Kim
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
Publication date: November 2018Source: European Journal of Surgical Oncology, Volume 44, Issue 11Author(s): Baek Kim, Diana Baxter, Andrew Hanby, Eldo Verghese, Andrew Sims, Thomas Hughes
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
Publication date: November 2018Source: European Journal of Surgical Oncology, Volume 44, Issue 11Author(s): Blossom Lake, Donna Appleton, Abel Zachariah, Habib Khan, Kerry Flemming, Jennifer Neill, Laura Pettit
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
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