A Combination of the Aerosolized PPAR- γ Agonist Pioglitazone and a Synthetic Surfactant Protein B Peptide Mimic Prevents Hyperoxia-Induced Neonatal Lung Injury in Rats

Conclusions: Nebulized PPAR- γ agonist PGZ with a synthetic lung surfactant accelerates lung maturation and prevents neonatal hyperoxia-induced lung injury more than either modality alone, with the potential to provide more effective prevention of BPD.Neonatology 2018;113:296 –304
Source: Neonatology - Category: Perinatology & Neonatology Source Type: research